quinolone

Suppliers

Names

[ CAS No. ]:
59-31-4

[ Name ]:
quinolone

[Synonym ]:
2-quinolone
quinolin-2(1H)-one
2-quinolinone
quinolin-2-one
2-Quinoline
2-hydroxyquinoline
EINECS 274-516-1
quinolinol
quinolone
2(1h)-quinolinone
2-oxoquinoline
quinolin-2-ol
Carbostyril
2-Quinolinol
hydroxyquinoline
MFCD00006743

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
352.9±15.0 °C at 760 mmHg

[ Melting Point ]:
198-199 °C(lit.)

[ Molecular Formula ]:
C9H7NO

[ Molecular Weight ]:
145.158

[ Flash Point ]:
167.2±20.4 °C

[ Exact Mass ]:
145.052765

[ PSA ]:
32.86000

[ LogP ]:
1.95

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.691

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
FG7175000

[ Packaging Group ]:
I; II; III

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-hydroxyquinolin-2-one
  • 2-Chloro-3-iodoquinoline
  • Ethyl trifluoroacetoacetate
  • Acetamide,N-(2-formylphenyl)-
  • 2-Propenamide,N,3-diphenyl-
  • quinoline 1-oxide
  • 7-dimethylamino-2-quinolone
  • β-chloro-isobutylamine
  • Benzyl bromide
  • Pentafluorobenzoyl chloride

DownStream

  • 1-ethenylquinolin-2-one
  • 1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]quinolin-2-one
  • 2-Hydroxyquinoline-3-carbaldehyde
  • 3,4-Dihydroquinolin-2(1H)-one
  • 5,6,7,8-tetrahydroquinolin-2-ol
  • 1,2,3,4-Tetrahydroquinoline
  • 2-Phenylquinoline
  • 2-(4-Methoxyphenyl)quinoline
  • 1-PHENYLNAPHTHALENE
  • Anisole, p-1-naphthyl- (6CI,7CI)

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Lipopolysaccharide Regulation of Intestinal Tight Junction Permeability Is Mediated by TLR4 Signal Transduction Pathway Activation of FAK and MyD88.

J. Immunol. 195 , 4999-5010, (2015)

Gut-derived bacterial LPS plays an essential role in inducing intestinal and systemic inflammatory responses and have been implicated as a pathogenic factor in necrotizing enterocolitis and inflammato...

CoFe2O4 nano-particles functionalized with 8-hydroxyquinoline for dispersive solid-phase micro-extraction and direct fluorometric monitoring of aluminum in human serum and water samples.

Anal. Chim. Acta 881 , 54-64, (2015)

A simple dispersive solid-phase micro-extraction method based on CoFe2O4 nano-particles (NPs) functionalized with 8-hydroxyquinoline (8-HQ) with the aid of sodium dodecyl sulfate (SDS) was developed f...

Atherosclerotic neovasculature MR imaging with mixed manganese-gadolinium nanocolloids in hyperlipidemic rabbits.

Nanomedicine: Nanotechnology, Biology, and Medicine 11(3) , 569-78, (2015)

A high r1 relaxivity manganese-gadolinium nanocolloid (αvβ3-MnOL-Gd NC) was developed and effectively detected atherosclerotic angiogenesis in rabbits fed cholesterol-rich diets for 12 months using a ...


More Articles

Related Compounds

  • Quinolone
  • 2-QUINOLONE
  • 4-quinolone
  • 2-QUINOLONE
  • 4-quinolone
  • 4-quinolone
  • 2-Chloro-5-(hexyloxy)-6-methoxy-4-methyl-8-quinolinamine
  • 2-Chloro-6-fluoro-4-(1h-pyrrolo[2,3-b]pyridin-4-yloxy)benzenamine
  • 2-Cyclopentyl-3,7-dihydro-5,6-dimethyl-7-(1-phenylethyl)-4h-pyrrolo[2,3-d]pyrimidin-4-one
  • 2-Hexenoic acid, 5-[[(1,1-dimethylethoxy)carbonyl]methylamino]-5-methyl-, (2e)-
  • 2-Methyl-2-propanesulfinic acid 4-chlorophenyl ester
  • 2-Methyl-4-(4-nitrophenoxy)pyridine
  • 2-Methyl-5-(trifluoromethyl)-1h-pyrrole-3-carboxylic acid methyl ester
  • 2-Oxo-[3,4-bipiperidine]-1-carboxylic acid 1,1-dimethylethyl ester
  • 3-(1-Methyl-4-piperidinyl)-5-(1-piperazinylmethyl)phenol trihydrochloride
  • 3-(2-Chloro-5-fluoro-4-pyrimidinyl)-3,8-diazabicyclo[3.2.1]octane
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