4-Hydroxy-2-butanone

Names

[ CAS No. ]:
590-90-9

[ Name ]:
4-Hydroxy-2-butanone

[Synonym ]:
2-Butanone, 4-hydroxy-
Methylolacetone
Monomethylolacetone
3-Ketobutan-1-ol
4-Hydroxy-2-butanone
4-Hydroxybutan-2-One
MFCD00059005
EINECS 209-693-6
3-Oxobutanol
3-Oxo-1-butanol

Chemical & Physical Properties

[ Density]:
1.023

[ Boiling Point ]:
156.3±13.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄H₈O₂

[ Molecular Weight ]:
88.105

[ Flash Point ]:
55.5±12.4 °C

[ Exact Mass ]:
88.052429

[ PSA ]:
37.30000

[ LogP ]:
-0.79

[ Vapour Pressure ]:
1.1±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.430

MSDS

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R10

[ Safety Phrases ]:
S16

[ RIDADR ]:
UN 1993

[ Hazard Class ]:
3.0

[ HS Code ]:
2914400090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2914400090

[ Summary ]:
2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Nanotube-supported bioproduction of 4-hydroxy-2-butanone via in situ cofactor regeneration.

Appl. Microbiol. Biotechnol. 94(5) , 1233-41, (2012)

Nicotinamide cofactor-dependent oxidoreductases have been widely employed during the bioproduction of varieties of useful compounds. Efficient cofactor regeneration is often required for these biotran...

Cu(I)-catalyzed reductive aldol cyclizations: diastereo- and enantioselective synthesis of beta-hydroxylactones.

Org. Lett. 7 , 4225, (2005)

[reaction: see text] Copper bisphosphine complexes catalyze the intramolecular reductive aldol reaction of alpha,beta-unsaturated esters with ketones, affording five- and six-membered beta-hydroxylact...

First experimental determination of the absolute gas-phase rate coefficient for the reaction of OH with 4-hydroxy-2-butanone (4H2B) at 294 K by vapor pressure measurements of 4H2B.

J. Phys. Chem. A 117(1) , 117-25, (2013)

The reaction of the OH radicals with 4-hydroxy-2-butanone was investigated in the gas phase using an absolute rate method at room temperature and over the pressure range 10-330 Torr in He and air as d...