Lidofenin

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Names

[ CAS No. ]:
59160-29-1

[ Name ]:
Lidofenin

[Synonym ]:
2-[carboxymethyl-[2-(2,6-dimethylanilino)-2-oxoethyl]amino]acetic acid
EINECS 261-636-4
MFCD00038399

Chemical & Physical Properties

[ Density]:
1.352 g/cm3

[ Boiling Point ]:
546.3ºC at 760 mmHg

[ Melting Point ]:
210ºC (dec.)(lit.)

[ Molecular Formula ]:
C14H18N2O5

[ Molecular Weight ]:
294.30

[ Flash Point ]:
284.2ºC

[ Exact Mass ]:
294.12200

[ PSA ]:
106.94000

[ LogP ]:
0.78610

[ Index of Refraction ]:
1.5110 (estimate)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AH1846000
CHEMICAL NAME :
Acetic acid, 2,2'-(N-(2,6-dimethylphenylcarbamoylmethyl)imino)di-
CAS REGISTRY NUMBER :
59160-29-1
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C14-H18-N2-O5
MOLECULAR WEIGHT :
294.34
WISWESSER LINE NOTATION :
QV1N1VQ1VMR B1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
88 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Cardiac - change in rate Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 6,1331,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJNMD9 European Journal of Nuclear Medicine. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1976- Volume(issue)/page/year: 3,41,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
168 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JNMEAQ Journal of Nuclear Medicine. (Samuel N. Turiel & Associates, Inc., 4 30 North Michigan Avenue, Chicago, IL, DElaware 7-3511) V.1- 1960- Volume(issue)/page/year: 18,997,1977

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26;S36

[ WGK Germany ]:
3

[ RTECS ]:
AH1846000

[ HS Code ]:
2924299090

Synthetic Route

Precursor & DownStream

Precursor

  • 2,6-xylidine

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • n-Methyl-4-(1h-1,2,4-triazol-1-yl)butan-1-amine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide