N-Butylurea

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Names

[ CAS No. ]:
592-31-4

[ Name ]:
N-Butylurea

[Synonym ]:
EINECS 209-748-4
Urea,butyl
1-Butylurea
MFCD00007956
Urea,N-butyl
butylamine amide
1-n-butylurea
N-BUTYLUREA

Chemical & Physical Properties

[ Density]:
0.962 g/cm3

[ Boiling Point ]:
179.4ºC at 760 mmHg

[ Melting Point ]:
95-98 °C(lit.)

[ Molecular Formula ]:
C5H12N2O

[ Molecular Weight ]:
116.16200

[ Flash Point ]:
62.3ºC

[ Exact Mass ]:
116.09500

[ PSA ]:
55.12000

[ LogP ]:
1.54600

[ Index of Refraction ]:
1.449

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YS3675000
CHEMICAL NAME :
Urea, butyl-
CAS REGISTRY NUMBER :
592-31-4
BEILSTEIN REFERENCE NO. :
1744775
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C5-H12-N2-O
MOLECULAR WEIGHT :
116.19
WISWESSER LINE NOTATION :
ZVM4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1255 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
382 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1285 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1627 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - somnolence (general depressed activity)
TYPE OF TEST :
Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Fibroblast
DOSE/DURATION :
4 gm/L/48H
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 48,337,1977

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R37;R68

[ Safety Phrases ]:
S45-S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
YS3675000

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Isocyanatobutane
  • S-methyl N-butylthiocarbamate
  • Potassium cyanate
  • n-butylamine
  • carbamoyl cyanide
  • N-Nitrocarbamide
  • Phenyl chlorothioformate
  • butylamine hydrochloride
  • N-Nitroso-N-methylurea

DownStream

  • 1,3-Dibutylurea
  • 2,4(1H,3H)-Pyrimidinedione,3-butyl-
  • 1-butyl-3-propan-2-ylurea
  • Tolbutamide
  • Urea,N-butyl-N'-phenyl-
  • 2-Propenamide,3-[[(butylamino)carbonyl]amino]-2-cyano-
  • 1-Butylpyrimidine-2,4(1H,3H)-dione
  • N-butyl-N-carbamoylbutanamide
  • Urea,N-butyl-N-nitroso-
  • 2,4(1H,3H)-Quinazolinedione,3-butyl-

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Related Compounds

  • N,N-di-n-butylurea
  • N,N'-Di-n-butylurea
  • N-Nitroso-N-butylurea
  • N-butyryl-N-butylurea
  • 1-benzyl-3-n-butylurea
  • 3-(3,4-Dichlorophenyl)-1-methyl-1-n-butylurea
  • 2,2-Dimethoxycyclobutane-1-sulfonamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 4-(4-{5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}piperazin-1-yl)-N-ethylpyrimidin-2-amine
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • N-Methyl-N-(oxetan-3-yl)pyrrolidin-3-amine
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde