2-Amino-5-chlorobenzonitrile

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Names

[ CAS No. ]:
5922-60-1

[ Name ]:
2-Amino-5-chlorobenzonitrile

[Synonym ]:
2-amino-5-chlorobenzenecarbonitrile
amino(2-) 5-chloro-benzonitrile
2-Amino-5-chloro-benzonitrile
5-chloro-anthranilonitrile
EINECS 227-651-5
MFCD00017106
Benzonitrile, 2-amino-5-chloro-
4-chloro-2-cyanoaniline
Benzonitrile,2-amino-5-chloro
2-Amino-5-chlorobenzonitrile
1-amino-2-cyano-4-chlorobenzene
anthranilonitrile, 5-chloro-
Anthranilonitrile,5-chloro

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
290.9±25.0 °C at 760 mmHg

[ Melting Point ]:
96-99 °C(lit.)

[ Molecular Formula ]:
C7H5ClN2

[ Molecular Weight ]:
152.581

[ Flash Point ]:
129.7±23.2 °C

[ Exact Mass ]:
152.014130

[ PSA ]:
49.81000

[ LogP ]:
2.32

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.610

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39

[ RIDADR ]:
3276

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2926909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Chlorobutane
  • aminobenzonitrile
  • N-(4-chloro-2-cyanophenyl)-2,2,2-trifluoroacetamide
  • METHYLMAGNESIUM BROMIDE
  • 5-Chloro-2-nitrobenzonitrile
  • 2-Amino-5-chlorobenzamide
  • 4-Chloro-2-iodoaniline
  • N-(4-chloro-2-iodophenyl)-2,2,2-trifluoroacetamide

DownStream

  • 2-(aminomethyl)-4-chloroaniline
  • 2-Amino-5-chlorobenzamide
  • 2,4-Quinazolinediamine,6-chloro-
  • 2-Amino-5-chlorobenzophenone
  • 7-chloro-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one
  • 2,4,6-Trichloroquinazoline
  • 5-CHLORO-2-METHYLAMINOBENZONITRILE
  • 2-(benzenecarboximidoyl)-4-chloroaniline
  • phenylmagnesium bromide
  • 6-Chloro-4-cyclopropyl-2(1H)-quinazolinone

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Density functional theory study of Fourier transform infrared and Raman spectra of 2-amino-5-chloro benzonitrile.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 71(2) , 465-70, (2008)

The vibrational spectra of 2-amino-5-chloro benzonitrile (ACB) have been obtained by density functional theory (DFT) calculations. Normal coordinate analysis has been carried out to support the vibrat...

Novel 2,2-dioxide-4,4-disubstituted-1,3-H-2,1,3-benzothiadiazines as non-nucleoside reverse transcriptase inhibitors.

Bioorg. Med. Chem. Lett. 10(2) , 193-5, (2000)

Benzothiadiazine non-nucleoside reverse transcriptase inhibitors (NNRTIs) of HIV have been synthesized via a novel process to afford active inhibitors, with the most potent compound exhibiting an IC90...


More Articles

Related Compounds

  • 2-Amino-5-bromo-3-chlorobenzonitrile
  • 2-amino-5-bromo-4-chlorobenzonitrile
  • 2-amino-5-bromo-6-chlorobenzonitrile
  • 2-amino-5-(2-bromoacetyl)-3-chlorobenzonitrile
  • 2-amino-5-[2-(tert-butylamino)-1-hydroxyethyl]-3-chlorobenzonitrile
  • 2-amino-5-(3-tert-butyl-1,3-oxazolidin-5-yl)-3-chlorobenzonitrile