Chlorofluoromethane
Suppliers
Names
[ CAS No. ]:
593-70-4
[ Name ]:
Chlorofluoromethane
[Synonym ]:
monofluoro boroxine
monofluorobenzene
4-fluorobenzene
Monofluorboroxin
1-fluorobenzene
p-fluorobenzene
monofluorochloromethane
2-fluorobenzene
Chlorofluoromethane
o-di-fluorobenzene
FLUOROBOROXIN
Fluorochloromethane
monochloromonofluoromethane
Chloro(fluoro)methane
Methane, chlorofluoro-
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
-10.8±8.0 °C at 760 mmHg
[ Melting Point ]:
-133ºC
[ Molecular Formula ]:
CH2ClF
[ Molecular Weight ]:
68.478
[ Flash Point ]:
-89.8±5.3 °C
[ Exact Mass ]:
67.982903
[ LogP ]:
0.78
[ Vapour Pressure ]:
2603.0±0.0 mmHg at 25°C
[ Index of Refraction ]:
1.304
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- PA6408000
- CHEMICAL NAME :
- Methane, chlorofluoro-
- CAS REGISTRY NUMBER :
- 593-70-4
- BEILSTEIN REFERENCE NO. :
- 1730796
- LAST UPDATED :
- 199801
- DATA ITEMS CITED :
- 16
- MOLECULAR FORMULA :
- C-H2-Cl-F
- MOLECULAR WEIGHT :
- 68.48
- WISWESSER LINE NOTATION :
- G1F
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 12635 mg/m3
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 10000 ppm/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10000 ppm/6H/2W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes Endocrine - other changes Blood - changes in spleen
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 78 gm/kg/1Y-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 10 pph
- REFERENCE :
- EVSRBT Environmental Science Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.1- 1972- Volume(issue)/page/year: 25,91,1982 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 41,229,1986 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 41,229,1986 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-GERMANY;Carcinogen JAN 1993 OEL-HUNGARY:TWA 100 mg/m3;STEL 200 mg/m3 JAN 1993 OEL-SWITZERLAND;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3008 No. of Facilities: 262 (estimated) No. of Industries: 5 No. of Occupations: 5 No. of Employees: 2705 (estimated) No. of Female Employees: 159 (estimated)
Safety Information
[ RIDADR ]:
UN 3163
[ Hazard Class ]:
2.2