1,1-DIMETHYLHYDRAZINE HYDROCHLORIDE

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Names

[ CAS No. ]:
593-82-8

[ Name ]:
1,1-DIMETHYLHYDRAZINE HYDROCHLORIDE

[Synonym ]:
1,1-dimethylhydrazine,hydrochloride

Chemical & Physical Properties

[ Density]:
0.829g/cm3

[ Boiling Point ]:
63.9ºC at 760mmHg

[ Melting Point ]:
85ºC

[ Molecular Formula ]:
C2H9ClN2

[ Molecular Weight ]:
96.55930

[ Flash Point ]:
1.1ºC

[ Exact Mass ]:
96.04540

[ PSA ]:
29.26000

[ LogP ]:
0.92400

[ Water Solubility ]:
almost transparency

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MV2900000
CHEMICAL NAME :
Hydrazine, 1,1-dimethyl-, hydrochloride
CAS REGISTRY NUMBER :
593-82-8
LAST UPDATED :
199410
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C2-H8-N2.Cl-H
MOLECULAR WEIGHT :
96.58
WISWESSER LINE NOTATION :
ZN1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
196 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
210 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
191 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
426 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - excitement Behavioral - rigidity (including catalepsy)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
466 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - excitement Behavioral - rigidity (including catalepsy)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
402 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - excitement Behavioral - rigidity (including catalepsy)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
96 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
35 gm/kg/73W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Human HeLa cell
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 13,2389,1992 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO HYDRAZINES-air:CA CL 0.03 ppm/120M REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992

Safety Information

[ Hazard Codes ]:
T+

[ Risk Phrases ]:
20/21-28

[ Safety Phrases ]:
22-36/37/39-45

[ RIDADR ]:
UN 2811

[ RTECS ]:
MV2900000

[ Packaging Group ]:
III

[ Hazard Class ]:
3.0

[ HS Code ]:
2928000090

Precursor & DownStream

Precursor

  • 1,2-dichlorohex-1-en-3-one
  • 1,1-Dimethylhydrazine
  • 1-(2-carbamylethyl)-1,1-dimethylhydrazinium chloride
  • N-Nitrosodimethylamine
  • B-chloro-di-n-butylborane

DownStream

  • Cyclopentanone,2,2-dimethylhydrazone
  • α-(Dimethylhydrazono)-4'-methylacetophenone
  • 4'-Chloro-α-(dimethylhydrazono)acetophenone
  • p-Methoxy-α-(dimethylhydrazono)acetophenone

Customs

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Related Compounds

  • 1,1-Dimethylhydrazine hydrochloride (1:1)
  • 1,1-Dimethylhydrazine hydrochloride (1:1)
  • 2-benzyl-1,1-dimethylhydrazine hydrochloride
  • 2-acridin-9-yl-1,1-dimethylhydrazine hydrochloride
  • 2-[1-(2-methoxyphenyl)propan-2-yl]-1,1-dimethylhydrazine hydrochloride
  • 2-(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)-1,1-DIMETHYLHYDRAZINE HYDROCHLORIDE
  • [1-(2-Bromo-6-chlorophenyl)cyclobutyl]methanamine
  • 1-(4-Bromo-2-chlorophenyl)cyclopentan-1-amine
  • 1-(5-Bromo-2-chlorophenyl)cyclopentan-1-amine
  • 1-(2-Bromo-5-chlorophenyl)cyclopentan-1-amine
  • N,N-Diethyl-2-thiazolecarboxamide
  • 3-(3-Bromo-2,4-difluorophenyl)-1,2-oxazol-5-amine
  • 5-(3-Bromo-2,4-difluorophenyl)-1,2-oxazol-3-amine
  • 5-(2-Bromo-4,5-difluorophenyl)-1,2-oxazol-3-amine
  • 3-(2-Bromo-4,5-difluorophenyl)-1,2-oxazol-5-amine
  • 2-(6-Bromobenzo[d][1,3]dioxol-5-yl)-2-hydroxyacetic Acid
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