EXAPROLOL HYDROCHLORIDE

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Names

[ CAS No. ]:
59333-90-3

[ Name ]:
EXAPROLOL HYDROCHLORIDE

[Synonym ]:
VULM 111 hydrochloride
Exaprolol hydrochloride
UNII-FGT82HNC7L
M.G. 8823
Exaprolol HCl

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₃₀ClNO₂

[ Molecular Weight ]:
327.88900

[ Exact Mass ]:
327.19700

[ PSA ]:
41.49000

[ LogP ]:
4.66490

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UA9813000

CHEMICAL NAME :: 2-Propanol, 1-(2-cyclohexylphenoxy)-3-((1-methylethyl)amino)-, hydrochloride

CAS REGISTRY NUMBER :: 59333-90-3

LAST UPDATED :: 198906

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C18-H29-N-O2.Cl-H

MOLECULAR WEIGHT :: 327.94

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1850 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,506,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 54 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,506,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 860 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,506,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 78 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,506,1976

Related Compounds

Tyrocidine, hydrochloride
Triprolidine hydrochloride
Minoxidil hydrochloride
Elacridar hydrochloride
dodecylamine hydrochloride
Azetidine, hydrochloride, homopolymer (9CI)
4-Phenyl-2,3-pyridinedicarboxylic acid
2-Methyl-5-(2-pyridyl)oxazole
6-Methoxy-2,3-dihydrobenzo[d]oxazole
6-(Tert-butyl)-1,2,3,4-tetrahydroisoquinoline
3-Methoxy-2-(methylamino)propanoic acid
2-{5-[(4-Methylphenoxy)methyl]furan-2-yl}-5-(4-phenylpiperazin-1-yl)-1,3-oxazole-4-carbonitrile
N-methyl-4-(phenylsulfonyl)-2-(p-tolyl)oxazol-5-amine
N-(3-morpholinopropyl)-4-(phenylsulfonyl)-2-(p-tolyl)oxazol-5-amine
N-(furan-2-ylmethyl)-4-(phenylsulfonyl)-2-(m-tolyl)oxazol-5-amine
4-((4-chlorophenyl)sulfonyl)-N-(3-methoxypropyl)-2-(p-tolyl)oxazol-5-amine

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