EXAPROLOL HYDROCHLORIDE

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Names

[ CAS No. ]:
59333-90-3

[ Name ]:
EXAPROLOL HYDROCHLORIDE

[Synonym ]:
VULM 111 hydrochloride
Exaprolol hydrochloride
UNII-FGT82HNC7L
M.G. 8823
Exaprolol HCl

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₃₀ClNO₂

[ Molecular Weight ]:
327.88900

[ Exact Mass ]:
327.19700

[ PSA ]:
41.49000

[ LogP ]:
4.66490

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UA9813000

CHEMICAL NAME :: 2-Propanol, 1-(2-cyclohexylphenoxy)-3-((1-methylethyl)amino)-, hydrochloride

CAS REGISTRY NUMBER :: 59333-90-3

LAST UPDATED :: 198906

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C18-H29-N-O2.Cl-H

MOLECULAR WEIGHT :: 327.94

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1850 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,506,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 54 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,506,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 860 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,506,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 78 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,506,1976

Related Compounds

Tyrocidine, hydrochloride
Triprolidine hydrochloride
Minoxidil hydrochloride
Elacridar hydrochloride
dodecylamine hydrochloride
Azetidine, hydrochloride, homopolymer (9CI)
Tert-butyl 2-(3,5-dichlorophenyl)-2-[(2,2,2-trifluoroethyl)amino]acetate
2-{[(Benzyloxy)carbonyl]amino}-4-(4-methoxyphenyl)thiophene-3-carboxylic acid
2-[(4-{[(tert-butoxy)carbonyl]amino}-3,5-dimethyl-1H-pyrazol-1-yl)methyl]benzoic acid
2-{[4-(3-Bromophenyl)-9-[(tert-butoxy)carbonyl]-1-oxa-9-azaspiro[5.5]undecan-4-yl]oxy}acetic acid
Tert-butyl 3-amino-2-(difluoromethyl)benzoate
Tert-butyl 4-methyl-2-[(pyrrolidin-3-yl)methyl]-1,3-thiazole-5-carboxylate
Tert-butyl 2-{5-azaspiro[3.5]nonan-8-yl}acetate
5-[(benzyloxy)carbonyl]-4-(4-fluorophenyl)-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridine-6-carboxylic acid
Tert-butyl 5-(3-fluorophenyl)-1-oxo-1lambda4-thiomorpholine-3-carboxylate
methyl (4R)-2-(2,3-dichlorophenyl)-1,3-thiazolidine-4-carboxylate

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