Hydroxocobalamin monohydrochloride

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Names

[ Name ]:
Hydroxocobalamin monohydrochloride

[Synonym ]:
hydroxocobalamin hydrochloride
cobalt [(2R,3S,4R,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2S)-1-[3-[(2R,3R,4Z,7S,9Z,12S,13S,14Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydro-1H-corrin-21-id-3-yl]propanoylamino]propan-2-yl] phosphate hydrate hydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₂H₈₉ClCoN₁₃O₁₅P

[ Molecular Weight ]:
1381.81

[ PSA ]:
432.85000

[ LogP ]:
7.23660

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
methanol: soluble10mg/mL at 20°C, clear, dark red

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

In vivo doses of butadiene epoxides as estimated from in vitro enzyme kinetics by using cob(I)alamin and measured hemoglobin adducts: an inter-species extrapolation approach.

Toxicol. Appl. Pharmacol. 281(3) , 276-84, (2014)

1,3-Butadiene (BD) is a rodent and human carcinogen. In the cancer tests, mice have been much more susceptible than rats with regard to BD-induced carcinogenicity. The species-differences are dependen...

Production benefits from pre- and post-lambing anthelmintic treatment of ewes on commercial farms in the southern North Island of New Zealand.

N. Z. Vet. J. 63 , 211-9, (2015)

To measure the magnitude and variability in production responses to anthelmintic treatments administered to adult ewes around lambing.Ewes carrying twin lambs, from sheep and beef farms (eight in Year...

Processing of alkylcobalamins in mammalian cells: A role for the MMACHC (cblC) gene product.

Mol. Genet. Metab. 97 , 260-266, (2009)

The MMACHC gene product of the cblC complementation group, referred to as the cblC protein, catalyzes the in vitro and in vivo decyanation of cyanocobalamin (vitamin B(12)). We hypothesized that the c...

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hydroxocobalamin
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