7-chloro-5-(2-fluorophenyl)-N-methyl-3H-1,4-benzodiazepin-2-amine

Names

[ CAS No. ]:
59467-61-7

[ Name ]:
7-chloro-5-(2-fluorophenyl)-N-methyl-3H-1,4-benzodiazepin-2-amine

[Synonym ]:
7-Chlor-5-<2-fluorphenyl>-2-methylamino-3H-1,4-benzodiazepin
7-Chlor-(2-fluorphenyl)-2-methylamino-3H-1,4-benzodiazepin
[7-Chloro-5-(2-fluoro-phenyl)-3H-benzo[e][1,4]diazepin-2-yl]-methyl-amine
7-Chloro-5-(2-fluorophenyl)-2-methylamino-3H-1,4-benzodiazepine

Chemical & Physical Properties

[ Density]:
1.31g/cm3

[ Boiling Point ]:
472.2ºC at 760 mmHg

[ Molecular Formula ]:
C16H13ClFN3

[ Molecular Weight ]:
301.74600

[ Flash Point ]:
239.4ºC

[ Exact Mass ]:
301.07800

[ PSA ]:
36.75000

[ LogP ]:
2.84160

[ Index of Refraction ]:
1.631

Synthetic Route

Precursor & DownStream

Precursor

  • N-Desalkylflurazepam
  • Titanium tetrachloride

DownStream

  • Midazolam
  • 7-Chloro-5-(2-fluorophenyl)-2-(N-nitrosomethylamino)-3H-1,4-benzodiazepine

Related Compounds

  • 8-methyl-3-(2-oxo-2-(4-(pyridin-2-yl)piperazin-1-yl)ethyl)-3H-pyrimido[5,4-b]indol-4(5H)-one
  • N-(3-chloro-4-methylphenyl)-3-{[4-(2-fluorophenyl)piperazin-1-yl]sulfonyl}thiophene-2-carboxamide
  • N-(4-chlorophenyl)-3-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}thiophene-2-carboxamide
  • N-(3-chloro-4-methylphenyl)-3-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}thiophene-2-carboxamide
  • 4-[3-(1,3-benzodioxol-5-yl)-1,2,4-oxadiazol-5-yl]-2-(3-methoxyphenyl)phthalazin-1(2H)-one
  • Ethyl 4-phenyl-3-[(3,4,5-trimethoxyphenyl)sulfamoyl]thiophene-2-carboxylate
  • Ethyl 3-[(2-ethoxyphenyl)sulfamoyl]-4-phenylthiophene-2-carboxylate
  • Ethyl 3-[(2,4-difluorophenyl)sulfamoyl]-4-(4-methylphenyl)thiophene-2-carboxylate
  • Ethyl 3-[(1,3-benzodioxol-5-ylamino)sulfonyl]-4-(4-methylphenyl)thiophene-2-carboxylate
  • Ethyl 3-{[4-(4-fluorophenyl)piperazin-1-yl]sulfonyl}-4-(4-methylphenyl)thiophene-2-carboxylate
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