2,2-Dimethylmalonic acid

Names

[ CAS No. ]:
595-46-0

[ Name ]:
2,2-Dimethylmalonic acid

[Synonym ]:
Propanedioic acid, 2,2-dimethyl-
MFCD00004193
Dimethylpropanedioic acid
Dimethylmalonic acid
Dimethyl-propanedioic acid
2,2-dimethylpropanedioic acid
EINECS 209-867-1

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
310.2±25.0 °C at 760 mmHg

[ Melting Point ]:
191-193 °C(lit.)

[ Molecular Formula ]:
C₅H₈O₄

[ Molecular Weight ]:
132.115

[ Flash Point ]:
155.6±19.7 °C

[ Exact Mass ]:
132.042252

[ PSA ]:
74.60000

[ LogP ]:
0.14

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.476

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

Dimethyl dimethylmalonate
Dimethyl malonate
Diethyl ether
Diethyl malonate
Neopentyl glycol
methyl iodide
3-tert-butyl-2,4,4-trimethyl-2-pentene
Isobutyric acid
Pivalic acid
2,2,5,5-tetraMethyl-1,3-dioxane-4,6-dione

DownStream

Dimethyl dimethylmalonate
2,2-dimethylphenalene-1,3-dione
(2,2-dimethyl-3-trimethylsilyloxypropoxy)-trimethylsilane
5,5-DimethylBarbituric Acid
2,2-Dimethyl-1,3-propanediamine
dimethylmalonyl chloride
(S,S)-(-)-2,2'-Isopropylidenebis(4-tert-butyl-2-oxazoline)
Neopentyl glycol
3-Methoxy-2,2-dimethyl-3-oxopropanoic acid
Isobutyric acid

Articles

Targeted metabolomics in the expanded newborn screening for inborn errors of metabolism.

Mol. Biosyst. 11 , 1525-35, (2015)

Inborn errors of metabolism are genetic disorders due to impaired activity of enzymes, transporters, or cofactors resulting in accumulation of abnormal metabolites proximal to the metabolic block, lac...

Method development in quantitative NMR towards metrologically traceable organic certified reference materials used as (31)P qNMR standards.

Anal. Bioanal. Chem 407 , 3115-3123, (2015)

Quantitative nuclear magnetic resonance (qNMR) spectroscopy is employed by an increasing number of analytical and industrial laboratories for the assignment of content and quantitative determination o...

Using high-performance ¹H NMR (HP-qNMR®) for the certification of organic reference materials under accreditation guidelines--describing the overall process with focus on homogeneity and stability assessment.

J. Pharm. Biomed. Anal. 93 , 102-110, (2014)

Quantitative NMR spectroscopy (qNMR) is gaining interest across both analytical and industrial research applications and has become an essential tool for the content assignment and quantitative determ...

2,2-Dimethylmalonic acid dibutyl ester
2,2-dimethylmalonic acid-tert-butyl ester
2,2-dimethylmalonic acid monobenzyl ester
2,2-dimethylmalonic acid benzyl tert-butyl ester
Dimethyl dimethylmalonate
2-Chlorocarbonyl-2-methyl-propionic acid ethylester
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]methyl}-4-methylcyclohexane-1-carboxylic acid
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide