N-Methyl-4-anisidine

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Names

[ CAS No. ]:
5961-59-1

[ Name ]:
N-Methyl-4-anisidine

[Synonym ]:
p-Anisidine, N-methyl-
1-Methylamino-4-methoxybenzene
N-Methyl-4-anisidine
EINECS 227-735-1
4-Methoxy-N-methylaniline
Benzenamine, 4-methoxy-N-methyl-
N-Methyl-p-anisidine
P-METHOXY-N-METHYLANILINE
MFCD00008399
N-Methyl-4-methoxyaniline
4-Methoxy-N-methylbenzenamine

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
252.4±0.0 °C at 760 mmHg

[ Melting Point ]:
33-36 °C(lit.)

[ Molecular Formula ]:
C8H11NO

[ Molecular Weight ]:
137.179

[ Flash Point ]:
87.2±12.1 °C

[ Exact Mass ]:
137.084061

[ PSA ]:
21.26000

[ LogP ]:
1.41

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.553

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Chloro-4-methoxybenzene
  • methylamine
  • Carbamic acid,N-(4-methoxyphenyl)-,ethyl ester
  • 4-Bromoanisole
  • p-Anisidine
  • methyl iodide
  • Formaldehyde
  • Formamide,N-(4-methoxyphenyl)-
  • 4-methoxy-N,N-dimethylaniline

DownStream

  • N-Methyl-N-(4-methoxyphenyl)-4-nitrobenzamide
  • Benzenamine, 2-ethenyl-4-methoxy-N-methyl- (9CI)
  • N-(4-hydroxyphenyl)-N-methyl-nitrous amide
  • 5-METHOXY-1-METHYL1H-INDOLE
  • 2-iodo-4-methoxy-N-methylaniline
  • 2H-INDOL-2-ONE, 1,3-DIHYDRO-5-HYDROXY-1,3-DIMETHYL-
  • 1-(4-methoxyphenyl)-1-methylhydrazine
  • 4,4'-dimethoxy-n-methyldiphenylamine
  • Metoquinone
  • N-(4-hydroxyphenyl)-N-methyl-benzamide

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Additive effects of amines on asymmetric hydrogenation of quinoxalines catalyzed by chiral iridium complexes.

Chemistry 18(37) , 11578-92, (2012)

The additive effects of amines were realized in the asymmetric hydrogenation of 2-phenylquinoxaline, and its derivatives, catalyzed by chiral cationic dinuclear triply halide-bridged iridium complexes...

Synthesis and structure-activity relationship studies in peripheral benzodiazepine receptor ligands related to alpidem.

Bioorg. Med. Chem. 16 , 3428-3437, (2008)

The exploration of the structure-affinity relationships concerning a new class of peripheral benzodiazepine receptor (PBR) ligands related to alpidem has been pursued in order to evaluate the consiste...


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Related Compounds

  • N-methyl-4-[[4-[methyl(oxiran-2-ylmethyl)amino]phenyl]methyl]-N-(oxiran-2-ylmethyl)aniline
  • N-methyl-4-(trichloromethyl)-6-(trifluoromethyl)-1,3,5-triazin-2-amine
  • N-methyl-4-(methylamino)-1,2,5-oxadiazole-3-carboxamide
  • N-METHYL-4-(PYRROLIDIN-1-YLMETHYL)BENZYLAMINE
  • N-methyl-4-(1-oxo-3-phenylinden-2-yl)benzenesulfonamide
  • N-Methyl-4-[5-(trifluoromethyl)pyridin-2-yl]benzylamine
  • 3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-5-methyl-2-(1-methylethyl)-, cis-
  • N-2-Benzothiazolyl-N-[5-[2-[3-(2-benzothiazolyl)-5-cyano-1-(1,1-dimethylethyl)-2,3-dihydro-1H-imidazol-4-yl]diazenyl]-4-methyl-6-[[(methylsulfonyl)amino]methyl]-2-pyridinyl]methanesulfonamide
  • 4-[2-[5-(Aminocarbonyl)-1-ethyl-1,2,3,6-tetrahydro-4-methyl-2,6-dioxo-3-pyridinyl]diazenyl]-6-[[4-[(3-amino-4-sulfophenyl)amino]-6-chloro-1,3,5-triazin-2-yl]amino]-1,3-benzenedisulfonic acid
  • 1H-Cyclonona[1,2-c:5,6-ca(2)]difuran-1,3,6-trione, 4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1R)-1-hydroxyheptyl]-10-[(S)-hydroxy[(2S)-tetrahydro-6-oxo-2H-pyran-2-yl]methyl]-, (4R,5S,10S)-rel-
  • 3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-6-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-5-[4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-oxobutyl]-1,4-dihydro-2-methyl-, methyl ester
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[[(1,1-dimethylethoxy)carbonyl]amino]phenylacetyl]amino]-3-(methylthio)-8-oxo-, diphenylmethyl ester, 5-oxide, [6R-[6I+/-,7I(2)(R*)]]-
  • [(3R,4S,5R,6R)-5-hydroxy-6-[4-hydroxy-3-[[4-hydroxy-3-(4-hydroxy-3-methylbut-2-enyl)benzoyl]amino]-8-methyl-2-oxochromen-7-yl]oxy-3-methoxy-2,2-dimethyloxan-4-yl] carbamate
  • 2-[(2R)-2-Amino-1-oxopropyl]-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-2-azabicyclo[2.2.2]octane-6-carboxamide
  • Butanoic acid, 3,3-dimethyl-, 6,7a-dihydro-4-[(3-hydroxy-3-methyl-1-oxobutoxy)methyl]-1-(3-methyl-1-oxobutoxy)spiro[cyclopenta[c]pyran-7(1H),2a(2)-oxiran]-6-yl ester, [1S-(1I+/-,6I+/-,7I(2),7aI+/-)]-
  • 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]propyl]-7-oxo-3-(tetrahydro-2-furanyl)-, 2-propenyl ester, [5S-[3(S*),5I+/-,6I+/-(S*)]]-
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