5'-o-trityl-2',3'-dehydrothymidine

Names

[ CAS No. ]:
5964-41-0

[ Name ]:
5'-o-trityl-2',3'-dehydrothymidine

[Synonym ]:
2',3'-Dehydro-5'-O-tritylthymidine
2',3'-Dehydro-5'-O-trityl-D-thymidine
5-methyl-1-(5-trityloxymethyl-2,5-dihydro-furan-2-yl)-1H-pyrimidine-2,4-dione
2',3'-didehydro-2',3'-dideoxy-5-methyl-5'-O-(triphenylmethyl)uridine
2',3'-didehydro-5'-O-trityl-3'-deoxythymidine
5'-O-trityl-d4T
5'-O-trityl-2',3'-thymidinene
3'-deoxy-2',3'-didehydrothymidine 5'-trityl ether
2,3-DIDEHYDRO-3-DEOXY-5-O-(TRIPHENYLMETHYL)-THYMIDINE(KEY INTERMEDIATE OF ZIDOVUDINE:AZT)
5'-O-trityl-3'-deoxy-2'-thymidinene

Chemical & Physical Properties

[ Density]:
1.24g/cm3

[ Molecular Formula ]:
C29H26N2O4

[ Molecular Weight ]:
466.52800

[ Exact Mass ]:
466.18900

[ PSA ]:
73.32000

[ LogP ]:
4.30730

[ Index of Refraction ]:
1.616

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • [(2R,3R,4R,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-4-methylsulfonyloxy-2-(trityloxymethyl)oxolan-3-yl] methanesulfonate
  • 3''-O-MESYL-5''-O-TRITYLTHYMIDINE
  • 5-O-Triphenylmethyl-2-deoxy-2,3-didehyrothymidine
  • Propylamine
  • Ethylamine
  • Allylamine
  • 5-Methyluridine

DownStream

  • Stavudine
  • 5-methyl-1-[(2R,4R)-4-(trityloxymethyl)-3,6-dioxabicyclo[3.1.0]hexan-2-yl]pyrimidine-2,4-dione

Related Compounds

  • 5-ethyl-3'-iodo-5'-O-trityl-2',3'-dideoxyuridine
  • 3'-azido-5-ethyl-5'-O-trityl-2',3'-dideoxyuridine
  • 5'-O-trityl-3'-(acetylthio)-2',3'-dideoxythymidine
  • 5'-O-TRITYL-2'-DEOXY-BETA-D-LYXOFURANOSYLTHYMINE
  • 5'-O-trityl-3'-deoxycytidine
  • 5'-O-trityl-3'-O-tert-butyldimethylsilyl thymidine
  • n1,n4-Dimethylbenzene-1,4-disulfonamide
  • 2,5-Dibenzylthiophene
  • 2-{[5-(pyridin-3-yl)-4-(1H-pyrrol-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-[3-(trifluoromethyl)phenyl]acetamide
  • [(1E)-1-Methyl-1-penten-1-yl]benzene
  • N-(benzo[d][1,3]dioxol-5-yl)-4,6-dimorpholino-1,3,5-triazin-2-amine hydrochloride
  • [2-(Difluoromethoxy)phenyl]methanesulfonyl chloride
  • Benzenemethanesulfonamide,2-(difluoromethoxy)-
  • Benzenemethanesulfonamide,2-[(dimethylamino)sulfonyl]-
  • Benzenesulfonamide,2-chloro-n-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]thioxomethyl]-
  • 2-(3,4-Dihydro-4-methyl-2H-1,4-benzothiazin-2-yl)-4-methoxyphenol
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