1,1-DIMETHYLUREA

Names

[ CAS No. ]:
598-94-7

[ Name ]:
1,1-DIMETHYLUREA

[Synonym ]:
1,1-dimethylurea
EINECS 202-498-7
MFCD00007959

Chemical & Physical Properties

[ Density]:
1.023g/cm3

[ Boiling Point ]:
130.4ºC at 760 mmHg

[ Melting Point ]:
178-183 °C(lit.)

[ Molecular Formula ]:
C₃H₈N₂O

[ Molecular Weight ]:
88.10840

[ Flash Point ]:
32.7ºC

[ Exact Mass ]:
88.06370

[ PSA ]:
46.33000

[ LogP ]:
0.32700

[ Index of Refraction ]:
1.452

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YS9867985

CHEMICAL NAME :: Urea, 1,1-dimethyl-

CAS REGISTRY NUMBER :: 598-94-7

BEILSTEIN REFERENCE NO. :: 1740666

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C3-H8-N2-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,1073,1969

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6610 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 54,188,1935

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
YS9867985

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

A synthesis of phosphorylated dioxohexahydropyrimidines from N,N'-dimethylurea, activated acetylenes, and trialkyl phosphites.

Mol. Divers. 14(4) , 617-20, (2010)

An efficient synthesis of alkyl 5-(dialkoxy- phosphoryl)-1,3-dimethyl-2, 6-dioxo-hexahydropyrimidine-4-carboxylates is described. This involves the reaction of N,N'-dimethylurea and dialkyl acetylendi...

Utilization of wheat straw for the preparation of coated controlled-release fertilizer with the function of water retention.

J. Agric. Food Chem. 60(28) , 6921-8, (2012)

With the aim of improving fertilizer use efficiency and minimizing the negative impact on the environment, a new coated controlled-release fertilizer with the function of water retention was prepared....

Denaturation behavior of alpha-chymotrypsinogen A in urea and alkylurea solutions: fluorescence studies.

J. Protein Chem. 13(3) , 323-31, (1994)

The solvent denaturation of alpha-chymotrypsinogen (alpha-ctg A) in aqueous solution of urea, methyl-, N,N'-dimethyl-, ethyl-, propyl- and butylurea was studied by fluorescence measurements. Data were...

1,1-Dimethylurea-d6
3-ethyl-1,1-dimethylurea
3-amino-1,1-dimethylurea
3-butyl-1,1-dimethylurea
3-hydroxy-1,1-dimethylurea
3-methoxy-1,1-dimethylurea
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(2-(1-Methyl-1H-pyrazol-4-yl)thiazol-4-yl)methanol
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
5-(1-Naphthyl)isoxazole-4-carboxylic acid
1H-pyrazolo[3,4-c]pyridin-4-amine
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde