Synephrine hydrochloride

Suppliers

Names

[ CAS No. ]:
5985-28-4

[ Name ]:
Synephrine hydrochloride

[Synonym ]:
UNII:EN5D1IH09S
DL-synephrine hydrochloride
EINECS 227-804-6
Synephrine HCl
4-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride
MFCD00050566
Synephrine hydrochloride
4-[1-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride (1:1)
2-methylamino-1-(4-hydroxyphenyl)-ethanol hydrochloride
Benzenemethanol, 4-hydroxy-α-[(methylamino)methyl]-, hydrochloride (1:1)
(+-)-1-(4-hydroxy-phenyl)-2-methylamino-ethanol,hydrochloride
Oxedrine hydrochloride
Ocuton (TN)
1-(4-Hydroxy-phenyl)-2-methylamino-aethanol,Hydrochlorid

Chemical & Physical Properties

[ Boiling Point ]:
341.1ºC at 760 mmHg

[ Melting Point ]:
147-150ºC

[ Molecular Formula ]:
C9H14ClNO2

[ Molecular Weight ]:
203.666

[ Flash Point ]:
163.4ºC

[ Exact Mass ]:
203.071304

[ PSA ]:
52.49000

[ LogP ]:
1.83790

[ Storage condition ]:
Refrigerator

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DO7700000
CHEMICAL NAME :
Benzyl alcohol, p-hydroxy-alpha-((methylamino)methyl)-, hydrochloride
CAS REGISTRY NUMBER :
5985-28-4
LAST UPDATED :
199712
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C9-H13-N-O2.Cl-H
MOLECULAR WEIGHT :
203.69
WISWESSER LINE NOTATION :
QR DYQ1M1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 71,62,1941
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 124,231,1927
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 124,231,1927

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2922199090

Precursor & DownStream

Precursor

DownStream

  • Compound A

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 3-[1-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride (1:1)
  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • Elacridar hydrochloride
  • dodecylamine hydrochloride