Dithizone
Suppliers
Names
[ CAS No. ]:
60-10-6
[ Name ]:
Dithizone
[Synonym ]:
(E)-N',2-Diphenyldiazenecarbothiohydrazide
Methanethione, [(E)-2-phenyldiazenyl](2-phenylhydrazinyl)-
Dithizone
Phenyldiazenecarbothioic Acid 2-Phenylhydrazide
MFCD00003025
diphenylthiocarbazone
EINECS 200-454-1
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
376.1±25.0 °C at 760 mmHg
[ Melting Point ]:
168°C (dec.)
[ Molecular Formula ]:
C13H12N4S
[ Molecular Weight ]:
256.33
[ Flash Point ]:
181.2±23.2 °C
[ Exact Mass ]:
256.078278
[ PSA ]:
80.87000
[ LogP ]:
4.01
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.644
[ Stability ]:
Stable. Incompatible with strong oxidizing agents.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LQ9450000
- CHEMICAL NAME :
- Formic acid, (phenylazo)thio-, 2-phenylhydrazide
- CAS REGISTRY NUMBER :
- 60-10-6
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C13-H12-N4-S
- MOLECULAR WEIGHT :
- 256.35
- WISWESSER LINE NOTATION :
- RNUNYUS&MMR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,44,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#07955 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80827 No. of Facilities: 260 (estimated) No. of Industries: 7 No. of Occupations: 9 No. of Employees: 1195 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80827 No. of Facilities: 69 (estimated) No. of Industries: 6 No. of Occupations: 7 No. of Employees: 2298 (estimated) No. of Female Employees: 1324 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S36-S26
[ RIDADR ]:
2811
[ RTECS ]:
LQ9450000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 169 , 16-24, (2015)
New biocides such as the organometallic compound zinc pyrithione (ZnP) have been massively introduced by many countries in formulations of antifouling paints following the ban on tributyltin (TBT). Th...
Adv. Healthc. Mater. 3(7) , 1061-70, (2014)
Clinical islet transplantation (CIT) has emerged as a promising treatment option for type 1 diabetes mellitus (T1DM); however, the antirejection drug regimen necessary to mitigate allograft islet reje...
Biomaterials 52 , 272-80, (2015)
There is a clinical need for an alternative labeling agent for magnetic resonance imaging (MRI) in islet transplantation. We aimed to evaluate the feasibility of islet MRI using ferumoxytol, which is ...