11beta-Hydroxyprogesterone

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Names

[ CAS No. ]:
600-57-7

[ Name ]:
11beta-Hydroxyprogesterone

[Synonym ]:
11BETA-HYDROXYPROGESTERONE
4-PREGNEN-11BETA-OL-3,20-DIONE
21-deoxycorticosterone
11B-HYDROXYPROGESTERONE
HYDROXYPROGESTERONE,11B
11beta-hydroxyprogesterone
4-PREGNEN-11BETA-3,20-DIONE

Chemical & Physical Properties

[ Density]:
1.15g/cm3

[ Boiling Point ]:
487.4ºC at 760 mmHg

[ Molecular Formula ]:
C21H30O3

[ Molecular Weight ]:
330.46100

[ Flash Point ]:
262.7ºC

[ Exact Mass ]:
330.21900

[ PSA ]:
54.37000

[ LogP ]:
3.69430

[ Index of Refraction ]:
1.557

[ Storage condition ]:
-20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TU5058000
CHEMICAL NAME :
Pregn-4-ene-3,20-dione, 11-beta-hydroxy-
CAS REGISTRY NUMBER :
600-57-7
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H30-O3
MOLECULAR WEIGHT :
330.51

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
28 mg/kg
SEX/DURATION :
female 28 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
JEMEAV Journal of Experimental Medicine. (Rockefeller Univ. Press, 1230 York Ave., New York, NY 10021) V.1- 1896- Volume(issue)/page/year: 102,347,1955

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • trimethylthioacetic S-acid
  • Hydrocortisone Valerate
  • 4-Pregnene-3,11,20-trione
  • 3,3,20,20-bis-ethanediyldioxy-pregn-5-en-11-one
  • Pregn-4-en-3,11,20-trion-3,20-bis-semicarbazon
  • Progesterone
  • 11β-Hydroxypregn-4-en-3,20-dion Bis-semicarbazon
  • 5β-pregnan-3α,11β-diol-20-one
  • 20,20-ethanediyldioxy-5β-pregnane-3α,11β-diol

DownStream

  • 4-Pregnene-3,11,20-trione
  • 5α-Dihydroprogesterone

Related Compounds

  • 11beta,21-dihydroxypregna-4,16-diene-3,20-dione 21-acetate
  • 11beta-Hydroxy-17,21-(tetrahydro-2H-pyran-2-ylidenedioxy)pregn-4-ene-3,20-dione
  • 11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17-benzoate
  • 11beta,13-Dihydrolactucin
  • 11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-octanoate
  • 11beta,17-dihydroxypregna-1,4-diene-3,20-dione 21-[(6-carboxycyclohex-3-en-1-yl)formate]