N-Isopropyl-N-nitroso-2-propanamine
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Names
[ CAS No. ]:
601-77-4
[ Name ]:
N-Isopropyl-N-nitroso-2-propanamine
[Synonym ]:
N-Isopropyl-N-nitrosopropan-2-amine
Diisopropyl-N-nitrosamine
Diisopropylnitrosamin
2-Propanamine,N-(1-methylethyl)-N-nitroso
Nitrosodiisopropylamine
Diisopropylnitrosamine
N-nitrosodiisopropyl amine
2-Propanamine, N- (1-methylethyl)-N-nitroso-
(i-propyl)2NNO
Diisopropylnitrosamin [German]
Diisopropylamine,N-nitroso
N-nitroso-N-(propan-2-yl)propan-2-amine
N-Isopropyl-N-nitroso-2-propanamine
2-Propanamine, N-(1-methylethyl)-N-nitroso-
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
194.5±0.0 °C at 760 mmHg
[ Melting Point ]:
>300ºC
[ Molecular Formula ]:
C6H14N2O
[ Molecular Weight ]:
130.188
[ Flash Point ]:
73.6±18.7 °C
[ Exact Mass ]:
130.110611
[ PSA ]:
32.67000
[ LogP ]:
1.12
[ Vapour Pressure ]:
0.6±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.453
[ Storage condition ]:
Refrigerator, Under Inert Atmosphere
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- IM4360000
- CHEMICAL NAME :
- Diisopropylamine, N-nitroso-
- CAS REGISTRY NUMBER :
- 601-77-4
- BEILSTEIN REFERENCE NO. :
- 0635986
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C6-H14-N2-O
- MOLECULAR WEIGHT :
- 130.22
- WISWESSER LINE NOTATION :
- 1Y1&NNO&&Y1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 850 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 14 gm/kg/110W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Blood - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1800 mg/kg/50W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Lungs, Thorax, or Respiration - tumors
MUTATION DATA
- TYPE OF TEST :
- Phage inhibition capacity
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 300 ug/well
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 260,349,1991 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-GERMANY;Carcinogen JAN 1993 OEL-SWITZERLAND;Carcinogen JAN 1993
Safety Information
[ Hazard Codes ]:
T+
[ Risk Phrases ]:
22-45
[ Safety Phrases ]:
53
[ RIDADR ]:
UN 2811
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)