TAUROLITHOCHOLIC ACID SODIUM SALT

Suppliers

Names

[ Name ]:
TAUROLITHOCHOLIC ACID SODIUM SALT

[Synonym ]:
sodium taurolithocholic acid
N-(3a-Hydroxy-5-cholan-24-oyl)taurine Monosodium Salt
sodium taurolithocholate
SODIUM TAUROLITHOCHOLATE SODIUM SALT
5BETA-CHOLANIC ACID-3ALPHA-OL 24-N-(2-SULFOETHYL)AMIDE SODIUM
taurolithocholic acid sodium
TAUROLITHIOCHOLIC ACID SODIUM

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₄₄NNaO₅S

[ Molecular Weight ]:
505.68600

[ Exact Mass ]:
505.28400

[ PSA ]:
114.91000

[ LogP ]:
5.55560

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Bile acid receptor TGR5 agonism induces NO production and reduces monocyte adhesion in vascular endothelial cells.

Arterioscler. Thromb. Vasc. Biol. 33(7) , 1663-9, (2013)

TGR5 is a G-protein-coupled receptor for bile acids. So far, little is known about the function of TGR5 in vascular endothelial cells.In bovine aortic endothelial cells, treatment with a bile acid hav...

Angiotensin II protects primary rat hepatocytes against bile salt-induced apoptosis.

PLoS ONE 7(12) , e52647, (2012)

Angiotensin II (AT-II) is a pro-fibrotic compound that acts via membrane-bound receptors (AT-1R/AT-2R) and thereby activates hepatic stellate cells (HSCs). AT-II receptor blockers (ARBs) are thus impo...

Bile acids induce pancreatic acinar cell injury and pancreatitis by activating calcineurin.

J. Biol. Chem. 288(1) , 570-80, (2013)

Biliary pancreatitis is the leading cause of acute pancreatitis in both children and adults. A proposed mechanism is the reflux of bile into the pancreatic duct. Bile acid exposure causes pancreatic a...

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