(±)-Glycidol

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Names

[ CAS No. ]:
60456-23-7

[ Name ]:
(±)-Glycidol

[Synonym ]:
(S)-(-)-2,3-epoxy-1-propanol
2-Oxiranylmethanol
(2S)-2-Oxiranylmethanol
(S)-(-)-2-(Hydroxymethyl)oxirane
2-Oxiranemethanol, (2S)-
(2S)-Oxiran-2-ylmethanol; (2S)-(-)-2,3-Epoxypropan-1-ol
(2S)-(-)-3-Hydroxy-1,2-propenoxide
MFCD00074874
(2S)-Oxiran-2-ylmethanol
(S)-(-)-Glycidol
[(2S)-oxiran-2-yl]methanol
(S)-Glycidol
Glycidol
UNII:S54CF1DV9A
(R,S)-Glycidol
oxiran-2-ylmethanol
(S)-(-)-1-hydroxy-2,3-epoxypropane
2-Oxiranemethanol
(±)-GLYCIDOL

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
162.4±8.0 °C at 760 mmHg

[ Molecular Formula ]:
C3H6O2

[ Molecular Weight ]:
74.078

[ Flash Point ]:
81.1±0.0 °C

[ Exact Mass ]:
74.036781

[ PSA ]:
32.76000

[ LogP ]:
-0.95

[ Vapour Pressure ]:
0.7±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.455

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RR0508100
CHEMICAL NAME :
Oxiranemethanol, (S)-
CAS REGISTRY NUMBER :
60456-23-7
BEILSTEIN REFERENCE NO. :
0079783
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C3-H6-O2
MOLECULAR WEIGHT :
74.09

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TYPE OF TEST :
Cytogenetic analysis
TYPE OF TEST :
Sister chromatid exchange

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
2500 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 278,289,1992

Safety Information

[ Symbol ]:

GHS05, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H312-H315-H318-H331-H335-H350-H360

[ Precautionary Statements ]:
P201-P261-P280-P305 + P351 + P338-P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R45;R60;R21/22;R23;R36/37/38;R68

[ Safety Phrases ]:
S53-S45

[ RIDADR ]:
UN 2810

[ WGK Germany ]:
3

[ RTECS ]:
RR0508100

[ Hazard Class ]:
6.1

[ HS Code ]:
2910900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Allyl alcohol
  • Glycidol
  • 3-Chloro-1,2-propanediol
  • (2S)-3-Chlorpropan-1,2-diol
  • Glycidyl butyrate
  • [(2S)-2,3-dihydroxypropyl] 4-methylbenzenesulfonate
  • (R)-Glycidyl butyrate
  • phenylacetate of 2,3-epoxypropan-1-ol
  • 3-BROMO-1,2-PROPANEDIOL

DownStream

  • (R)-Glycidyl butyrate
  • (R)-(-)-1,2-Propanediol
  • (S)-(+)-Glycidyl-4-nitrobenzoate
  • (S)-(+)-Glycidyl-4-nitrobenzoate
  • (R)-3-Amino-1,2-Propanediol
  • (S)-Glycidyl tosylate
  • (2R)-2-[(Trityloxy)methyl]oxirane
  • (2R)-2-(Methoxymethyl)oxirane
  • (R)-Propafenone
  • (R)-(-)-Benzyl glycidyl ether

Customs

[ HS Code ]: 2910900090

[ Summary ]:
2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Direct Determination of MCPD Fatty Acid Esters and Glycidyl Fatty Acid Esters in Vegetable Oils by LC-TOFMS.

J. Am. Oil Chem. Soc. 88(1) , 1-14, (2011)

Analysis of MCPD esters and glycidyl esters in vegetable oils using the indirect method proposed by the DGF gave inconsistent results when salting out conditions were varied. Subsequent investigation ...

Cross metathesis as a general strategy for the synthesis of prostacyclin and prostaglandin analogues.

Org. Lett. 8 , 3101, (2006)

[reaction: see text] A cross metathesis (CM) approach has been successfully applied to introduce fully functionalized omega-side chain appendages of various prostacyclin and prostaglandin analogues, r...


More Articles

Related Compounds

  • (±)-GLYCIDOL
  • (±)-GLYCIDOL
  • (±)7(8)-DiHDPA
  • (±)-Amiflamine
  • (±)13(14)-EpDPA
  • (±)-Equol
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  • 1H-Benzimidazole-2-ethanamine, 6-(trifluoromethyl)-
  • Dimethyl 4-[[tert-butyl(dimethyl)silyl]oxymethyl]cyclohexane-1,1-dicarboxylate
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1-(2-Dibenzylamino-phenyl)-cyclopropanol
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 1-((3-Bromothiophen-2-yl)methyl)cyclopropane-1-carboxylic acid
  • 1-(5-Bromo-1H-benzo[d]imidazol-2-yl)-3-methylbutan-1-amine