Olsalazine (Disodium)

Suppliers

Names

[ Name ]:
Olsalazine (Disodium)

[Synonym ]:
Azodisal sodium
3,3'-(E)-diazène-1,2-diylbis(6-hydroxybenzoate) de disodium
Benzoic acid, 3,3'-azobis[6-hydroxy-, disodium salt
Benzoic acid, 3,3'-[(E)-1,2-diazenediyl]bis[6-hydroxy-, sodium salt (1:2)
Olsalazine Sodium Salt
Dipentum
EINECS 227-975-7
Disodium 3,3'-[(E)-1,2-diazenediyl]bis(6-hydroxybenzoate)
Olsalazine disodium
Dinatrium-3,3'-(E)-diazen-1,2-diylbis(6-hydroxybenzolcarboxylat)
Disodium 3,3'-(E)-diazene-1,2-diylbis(6-hydroxybenzoate)
MFCD00013300
Olsalazine (Disodium)

Chemical & Physical Properties

[ Boiling Point ]:
557.9ºC at 760 mmHg

[ Melting Point ]:
240ºC

[ Molecular Formula ]:
C₁₄H₈N₂Na₂O₆

[ Molecular Weight ]:
346.203

[ Flash Point ]:
291.2ºC

[ Exact Mass ]:
346.017761

[ PSA ]:
145.44000

[ LogP ]:
0.24020

[ Storage condition ]:
-20°C Freezer

Safety Information

[ HS Code ]:
2928000090

Customs

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Treatment of ulcerative colitis with oral mesalamine: advances in drug formulation, efficacy expectations and dose response, compliance, and chemoprevention.

Rev. Gastroenterol. Disord. 6(2) , 97-105, (2006)

Sulfasalazine, olsalazine, balsalazide, delayed-release mesalamine, controlled-release mesalamine, mesalamine pellets, and Multi-Matrix System mesalamine are effective first-line therapies for the tre...

Efficacy of drugs used in the treatment of IBD and combinations thereof in acute DSS-induced colitis in mice.

Life Sci. 92(12) , 708-18, (2013)

Although acute dextran sodium sulphate (DSS)-induced colitis in mice is frequently used as a preclinical model for testing drugs involved in inflammatory bowel disease (IBD), only limited data is avai...

Study of the plasma pharmacokinetics and faecal excretion of the prodrug olsalazine and its metabolites after oral administration to horses.

J. Vet. Pharmacol. Ther. 25(2) , 135-43, (2002)

Olsalazine sodium (Dipentum*) has been used therapeutically against inflammatory bowel disease in human medicine as an alternative to sulphasalazine over the past 20 years. Bacteria in the colon split...