(S)-2-AMINO-4-(2-AMINO-3-HYDROXYPHENYL)-4-OXOBUTANOIC ACID

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Names

[ CAS No. ]:
606-14-4

[ Name ]:
(S)-2-AMINO-4-(2-AMINO-3-HYDROXYPHENYL)-4-OXOBUTANOIC ACID

[Synonym ]:
rac 3-Hydroxy Kynurenine
(S)-2-Amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid
Paralysin II
REF DUPL: DL-3-Hydroxykynurenine

Chemical & Physical Properties

[ Density]:
1.461g/cm3

[ Boiling Point ]:
519.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₂N₂O₄

[ Molecular Weight ]:
224.21300

[ Flash Point ]:
267.9ºC

[ Exact Mass ]:
224.08000

[ PSA ]:
126.64000

[ LogP ]:
1.24060

[ Index of Refraction ]:
1.661

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY6650000

CHEMICAL NAME :: Alanine, 3-(3-hydroxyanthraniloyl)-, L-

CAS REGISTRY NUMBER :: 606-14-4

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C10-H12-N2-O4

MOLECULAR WEIGHT :: 224.24

WISWESSER LINE NOTATION :: ZR BQ FV1YZVQ -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4408 mg/kg/21D-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - bronchiogenic carcinoma

REFERENCE :: JCROD7 Journal of Cancer Research and Clinical Oncology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.93- 1979- Volume(issue)/page/year: 96,163,1980

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 160 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - facilitates action of known carcinogen

REFERENCE :: ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 108,924,1963

Safety Information

[ HS Code ]:
2922509090

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
3-[5-(2-Iodophenyl)-1,3,4-oxadiazol-2-yl]propanoic acid
N-(2-(3,5-dimethyl-1H-pyrazol-1-yl)ethyl)-2-(m-tolyl)acetamide
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine