4-AMINO-N-CYCLOPROPYL-3,5-DICHLOROBENZAMIDE

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Names

[ CAS No. ]:
60676-83-7

[ Name ]:
4-AMINO-N-CYCLOPROPYL-3,5-DICHLOROBENZAMIDE

[Synonym ]:
4-Amino-3,5-Dichloro-N-Cyclopropyl-Benzamide
N-Cyclopropyl-3,5-dichloro-4-aminobenzamide
4-Amino-3,5-dichloro-N-cyclopropylbenzamide
3.5-Dichlor-4-amino-N-cyclopropyl-benzamid
3.5-Dichlor-4-amino-benzoesaeure-cyclopropylamid
4-amino-N-cyclopropyl-3,5-dichlorobenzamide
MR-1230
N-Cyclopropyl-4-amino-3,5-dichlorobenzamide
Benzamide, 4-amino-3,5-dichloro-N-cyclopropyl-

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
346.0±42.0 °C at 760 mmHg

[ Melting Point ]:
174-175ºC

[ Molecular Formula ]:
C10H10Cl2N2O

[ Molecular Weight ]:
245.105

[ Flash Point ]:
163.0±27.9 °C

[ Exact Mass ]:
244.017014

[ PSA ]:
55.12000

[ LogP ]:
2.80

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.636

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CV0700000
CHEMICAL NAME :
Benzamide, 4-amino-N-cyclopropyl-3,5-dichloro-
CAS REGISTRY NUMBER :
60676-83-7
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C10-H10-Cl2-N2-O
MOLECULAR WEIGHT :
245.12
WISWESSER LINE NOTATION :
L3TJ AMVR DZ CG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
170 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,400,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,400,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
195 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,400,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
265 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,528,1963

Safety Information

[ HS Code ]:
2924299090

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds

  • 2-Amino-N-cyclopropyl-3,5-dichlorobenzamide
  • 4-Amino-N-cyclobutyl-3,5-dichlorobenzamide
  • 4-amino-N-(3,5-dibromo-4-methylamino-phenyl)benzenesulfonamide
  • 4-amino-N-(3,5-dichlorophenyl)benzenesulfonamide
  • 4-amino-N-(3-((5-chloro-4-(1-(phenylsulfonyl)-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
  • 4-amino-N-[3-(5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-11-ylidene)propyl]-N-methylbutanamide