[3-chloro-4-(phenylmethoxy)phenyl]acetic acid

Suppliers

Names

[ CAS No. ]:
60736-70-1

[ Name ]:
[3-chloro-4-(phenylmethoxy)phenyl]acetic acid

[Synonym ]:
VUFB9682
3-Chloro-4-benzyloxyphenylacetic acid
Benzofenac
EINECS 262-396-3
[3-chloro-4-(phenylmethoxy)phenyl]acetic acid
Acetic acid,(4-(benzyloxy)-3-chlorophenyl)
4-Benzyloxy-3-chlorophenylacetic acid
3-Chloro-4-(phenylmethoxy)benzeneacetic acid
3-chloro-4-benzylphenylacetic acid

Chemical & Physical Properties

[ Density]:
1.295g/cm3

[ Boiling Point ]:
442.8ºC at 760 mmHg

[ Molecular Formula ]:
C15H13ClO3

[ Molecular Weight ]:
276.71500

[ Flash Point ]:
221.6ºC

[ Exact Mass ]:
276.05500

[ PSA ]:
46.53000

[ LogP ]:
3.54610

[ Index of Refraction ]:
1.603

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CY1576540
CHEMICAL NAME :
Benzeneacetic acid, 3-chloro-4-(phenylmethoxy)-
CAS REGISTRY NUMBER :
60736-70-1
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C15-H13-Cl-O3
MOLECULAR WEIGHT :
276.73
WISWESSER LINE NOTATION :
QV1R CG DO1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2820 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 7,149,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1960 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 7,149,1982

Safety Information

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • methyl 4-Benzyloxy-3-Chlorophenylacetate
  • 2-Chloroanisole
  • 3-CHLORO-4-METHOXYBENZYL CHLORIDE
  • 3-CHLORO-4-METHOXYBENZENEACETONITRILE
  • Methyl (3-chloro-4-hydroxyphenyl)acetate
  • Benzyl chloride

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • [3-Chloro-4-(trifluoromethyl)phenyl]acetic acid
  • [3-Chloro-4-(methylsulfanyl)phenyl]acetic acid
  • 3-Chloro-4-isobutylphenylacetic acid
  • [3-Chloro-4-(2-methyl-4-oxo-4H-quinazolin-3-yl)-phenyl]-acetic acid ethyl ester; hydrochloride
  • (3-chloro-4-formylphenyl)acetic acid methyl ester
  • (3-chloro-4-hydrazinocarbonylphenyl)acetic acid methyl ester
  • 3-(4-fluoro-3-nitrophenyl)-1-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea
  • N-(2,5-diaza-2-(2-(2-methylphenyl)-2-oxoethyl)-3-oxo-6-phenylbicyclo[5.4.0]undeca-1(7),5,8,10-tetraen-4-yl)((2-methoxy-5-nitrophenyl)amino)formamide
  • 1,3-Bis(4-methyl-2,6-bis((R)-1-phenylethyl)phenyl)-1H-imidazol-3-ium chloride
  • 1-[4-Chloro-5-(trifluoromethyl)pyridin-3-YL]ethanone
  • Ethyl 2',5'-dioxospiro[bicyclo[3.1.0]hexane-2,4'-imidazolidine]-6-carboxylate
  • 5-fluoro-2-mercapto-3-phenylquinazolin-4(3H)-one
  • (2R,3R,4S,5R)-2-[6-[2-(4-amino-3,5-diiodophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
  • 1-(4-Chloro-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[2,3-b]pyridin-5-yl)ethanone
  • L-Proline, 1-[N-(tetrahydro-2-oxo-5-phenyl-3-furanyl)-L-alanyl]-
  • (S)-2-((S)-2-((S)-2-Amino-3-(1H-indol-3-yl)propanamido)-3-hydroxypropanamido)-3-phenylpropanoic acid
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.