1,1'-Pentamethylenebis[3-(2-chloroethyl)-3-nitrosourea]

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Names

[ CAS No. ]:
60784-44-3

[ Name ]:
1,1'-Pentamethylenebis[3-(2-chloroethyl)-3-nitrosourea]

Chemical & Physical Properties

[ Density]:
1.43g/cm3

[ Molecular Formula ]:
C11H20Cl2N6O4

[ Molecular Weight ]:
371.22000

[ Exact Mass ]:
370.09200

[ PSA ]:
130.52000

[ LogP ]:
2.42910

[ Index of Refraction ]:
1.581

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YT9955000
CHEMICAL NAME :
Urea, 1,1'-pentamethylenebis(3-(2-chloroethyl)-3-nitroso-
CAS REGISTRY NUMBER :
60784-44-3
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C11-H20-Cl2-N6-O4
MOLECULAR WEIGHT :
371.27
WISWESSER LINE NOTATION :
ONN2GVM5MVNNO&2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
45 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Liver - hepatitis (hepatocellular necrosis), diffuse Blood - changes in bone marrow (not otherwise specified)
TYPE OF TEST :
Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :
Gene conversion and mitotic recombination
TEST SYSTEM :
Yeast - Saccharomyces cerevisiae
DOSE/DURATION :
500 umol/L/16H
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 42,45,1977

Related Compounds

  • tert-Butyl (R)-(5,6,7,8-tetrahydroquinolin-8-yl)carbamate
  • 2-Methyl-5-(trifluoromethyl)pyridine-3-sulfonyl chloride
  • 1-Ethyl-1,7-diazaspiro[4.4]nonane
  • (3S,4S)-1-Boc-4-amino-piperidine-3-carboxylic acid ethyl ester
  • 2-Bromo-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(1H)-one
  • (S)-1-Oxa-6-azaspiro[3.4]octane
  • (R)-1-Oxa-6-azaspiro[3.4]octane
  • (R)-Tert-butyl3-((ethylamino)methyl)piperidine-1-carboxylate
  • [1-(2-Methyl-2,3-dihydro-1-benzofuran-5-yl)cyclopropyl]methanamine
  • (S)-4-Benzyl 2-methyl morpholine-2,4-dicarboxylate
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