1,1'-Hexamethylenebis[3-(2-chloroethyl)-3-nitrosourea]
Suppliers
Names
[ CAS No. ]:
60784-45-4
[ Name ]:
1,1'-Hexamethylenebis[3-(2-chloroethyl)-3-nitrosourea]
[Synonym ]:
1,1'-Hexamethylenebis-cnu
Chemical & Physical Properties
[ Density]:
1.4g/cm3
[ Molecular Formula ]:
C12H22Cl2N6O4
[ Molecular Weight ]:
385.24700
[ Exact Mass ]:
384.10800
[ PSA ]:
130.52000
[ LogP ]:
2.81920
[ Index of Refraction ]:
1.575
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YT4565000
- CHEMICAL NAME :
- Urea, 1,1'-hexamethylenebis(3-(2-chloroethyl)-3-nitroso-
- CAS REGISTRY NUMBER :
- 60784-45-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C12-H22-Cl2-N6-O4
- MOLECULAR WEIGHT :
- 385.30
- WISWESSER LINE NOTATION :
- ONN2GVM6MVNNO&2G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
MUTATION DATA
- TYPE OF TEST :
- Gene conversion and mitotic recombination
- TEST SYSTEM :
- Yeast - Saccharomyces cerevisiae
- DOSE/DURATION :
- 500 umol/L/16H
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 42,45,1977