5-Methylindoline-2,3-dione
Suppliers
Names
[ CAS No. ]:
608-05-9
[ Name ]:
5-Methylindoline-2,3-dione
[Synonym ]:
EINECS 210-152-1
5-Methyl-1H-indole-2,3-dione
5-Methylisatin
1H-Indole-2,3-dione, 5-methyl-
MFCD00005721
5-methylindoline-2,3-dione
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Melting Point ]:
180 °C (dec.)(lit.)
[ Molecular Formula ]:
C9H7NO2
[ Molecular Weight ]:
161.157
[ Exact Mass ]:
161.047684
[ PSA ]:
46.17000
[ LogP ]:
1.02
[ Index of Refraction ]:
1.598
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NL7939300
- CHEMICAL NAME :
- Indole-2,3-dione, 5-methyl-
- CAS REGISTRY NUMBER :
- 608-05-9
- BEILSTEIN REFERENCE NO. :
- 0123738
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C9-H7-N-O2
- MOLECULAR WEIGHT :
- 161.17
- WISWESSER LINE NOTATION :
- T56 BMVVJ G1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 790 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,858,1981
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
NL7939300
[ HS Code ]:
2933790090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Chromatogr. A. 562(1-2) , 279-87, (1991)
A simple procedure based upon capillary column gas chromatography-mass spectrometry (GC-MS) is described for the detection and determination of isatin (indole-2,3-dione) in body fluids and tissues. Af...
Biochem. Pharmacol. 57(8) , 913-5, (1999)
Isatin is an endogenous indole and an inhibitor of atrial natriuretic peptide (ANP) receptors coupled with particulate guanylyl cyclase (GC). In this study, several isatin analogues were tested as inh...
Rev. Med. Chir. Soc. Med. Nat. Iasi. 100(1-2) , 167-71, (1996)
This paper presents the synthesis of six hydrazones obtained by treating 5-methyl-isatin or 1-morpholino methyl-5-methyl-isatin with 3-(R-phenyl)-6-hydrazino-pyridazine (R = OCH3, Cl, Br) and two comp...