(2S)-3-Chlorpropan-1,2-diol

Suppliers

Names

[ Name ]:
(2S)-3-Chlorpropan-1,2-diol

[Synonym ]:
(S)-3-Chloro-1,2-propanediol
1,2-Propanediol, 3-chloro-, (S)-
EINECS 202-492-4
Q1YQ1G &&S Form
(2S)-3-chloropropane-1,2-diol
(2S)-3-Chloro-1,2-propanediol
1,2-Propanediol, 3-chloro-, (2S)-
MFCD00210270
(2S)-3-Chlorpropan-1,2-diol
(S)-(+)-3-chloro-1,2-propanediol
S-2-Chloro-1,2-propanediol

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
213.0±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃H₇ClO₂

[ Molecular Weight ]:
110.539

[ Flash Point ]:
113.3±21.8 °C

[ Exact Mass ]:
110.013458

[ PSA ]:
40.46000

[ LogP ]:
-0.76

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.474

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TY4202300

CHEMICAL NAME :: 1,2-Propanediol, 3-chloro-, (S)-

CAS REGISTRY NUMBER :: 60827-45-4

LAST UPDATED :: 198910

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C3-H7-O2

MOLECULAR WEIGHT :: 75.10

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 45500 ug/kg

SEX/DURATION :: male 14 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)

REFERENCE :: JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 51,105,1977

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H312-H318

[ Precautionary Statements ]:
P280-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R21;R23/25;R36/37/38;R62;R68

[ Safety Phrases ]:
S26-S28-S39-S45-S36/37/39

[ RIDADR ]:
UN 2689 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
TY4202300

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2905590090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Epichlorohydrin
1-chloro-3-hydroxypropan-2-one
(S)-(+)-Epichlorhydrin
ALLYL CHLORIDE
(S)-1,2-Diacetoxy-3-chloropropane
3-Chloro-1,2-propanediol
1-CHLOROMETHYL-1,2-ETHANEDIOL DIACETATE

DownStream

(5r)-3-(4-bromo-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one
(±)-Glycidol
(2R)-(-)-Glycidyl tosylate
(S)-Glycidyl nosylate

Customs

[ HS Code ]: 2905590090

[ Summary ]:
2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Complete detoxification of tris(1,3-dichloro-2-propyl) phosphate by mixed two bacteria, Sphingobium sp. strain TCM1 and Arthrobacter sp. strain PY1.

J. Biosci. Bioeng. 113(1) , 79-83, (2012)

Tris(1,3-dichloro-2-propyl) phosphate (TDCPP), a flame retardant, is regarded as a potentially toxic and persistent environmental contaminant. We previously isolated a TDCPP-degrading bacterium, Sphin...

Passage of MHPG from plasma to CSF in a non-human primate.

Rev. Med. Chir. Soc. Med. Nat. Iasi. 115(4) , 1278-82, (2011)

In experimental protocols with humans and non-human primates, cerebrospinal fluid (CSF) concentrations of 3-methoxy-4-hydroxyphenylethylene glycol (MHPG), the predominant end-product of norepinephrine...

Fatty acid esters of monochloropropanediol (MCPD) and glycidol in refined edible oils.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 30(1) , 46-51, (2013)

Recently, fatty acid esters of monochloropropanediol (MCPD) and that of glycidol have been reported in refined edible oils. Since then a wealth of research has been published on the factors influencin...

(2S)-3-heptadecoxypropane-1,2-diol
(2S)-3,3-dichloropropane-1,2-diol
(2S)-3-(4-phenylmethoxyphenyl)propane-1,2-diol
(2S)-3-(4-methoxyphenoxy)propane-1,2-diol
(2S)-3-(12-bromododecoxy)propane-1,2-diol
(2S)-3-(12-hydroxydodecoxy)propane-1,2-diol
N-(1-(benzo[d]thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)cyclohexanecarboxamide
1-methyl-N-(oxan-4-yl)piperidin-4-amine
Methyl (tetrahydro-2H-pyran-4-yl)-L-valinate
4-[4-(4-fluorophenyl)piperazin-1-yl]-N-[(2Z)-4-methyl-1,3-thiazol-2(3H)-ylidene]-4-oxobutanamide
5-bromo-N-[2-(propan-2-yl)-1H-benzimidazol-5-yl]furan-2-carboxamide
methyl 5-fluoro-2-({[4-(pyridin-2-yl)-1,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridin-5-yl]carbonyl}amino)benzoate
1-methyl-N-(oxan-4-yl)-1H-pyrazol-4-amine
3-[(5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)sulfanyl]-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one
1-ethyl-N-(oxan-4-yl)-1H-pyrazol-4-amine
N-[(2E)-5-cyclopropyl-1,3,4-thiadiazol-2(3H)-ylidene]-5-[4-(4-fluorophenyl)piperazin-1-yl]-5-oxopentanamide

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.