2-bromo-2',4'-dimethoxyacetophenone

Names

[ CAS No. ]:
60965-26-6

[ Name ]:
2-bromo-2',4'-dimethoxyacetophenone

[Synonym ]:
2-bromo-1-(2,4-dimethoxyphenyl)ethanone
EINECS 262-542-6
MFCD00000197

Chemical & Physical Properties

[ Density]:
1.422g/cm3

[ Boiling Point ]:
348.2ºC at 760 mmHg

[ Melting Point ]:
102-104 °C(lit.)

[ Molecular Formula ]:
C₁₀H₁₁BrO₃

[ Molecular Weight ]:
259.09700

[ Flash Point ]:
164.4ºC

[ Exact Mass ]:
257.98900

[ PSA ]:
35.53000

[ LogP ]:
2.28140

[ Index of Refraction ]:
1.542

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S27-S37/39

[ RIDADR ]:
1759

[ WGK Germany ]:
3

[ HS Code ]:
2914700090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

4-(2,4-DIMETHOXY-PHENYL)-THIAZOL-2-YLAMINE
2',4'-dimethoxyacetophenone
1-(2,4-dimethoxyphenyl)-2-[(4-methoxyphenyl)methylsulfanyl]ethanone
1-(2,4-dimethoxyphenyl)-2-tritylsulfanylethanone
6-(2,4-dimethoxyphenyl)imidazo[2,1-b][1,3]thiazole
6-(2,4-dimethoxyphenyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole
2-(2,4-dimethoxyphenyl)imidazo[1,2-a]pyrazine
2-chloro-1-(2,4-dimethoxyphenyl)ethanone

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Articles

Conversion of the active-site cysteine residue of papain into a dehydro-serine, a serine and a glycine residue.

Eur. J. Biochem. 84(1) , 293-9, (1978)

Photolysis of papain which had been inhibited with 2-bromo-2',4'-dimethoxyacetophenone regenerated papain, but also formed [deltaSer25]-papain (i.e. papain in which the active-site cysteine residue 25...

2-bromo-2',4'-dichloroacetophenone
2-Bromo-2',4',6'-triisopropyl-3,6-dimethoxy-1,1'-biphenyl
2-bromo-2',4',6'-trimethylpropiophenone
2-Bromo-2',4',6'-triisopropyl-3-methoxy-6-methyl-1,1'-biphenyl
2-Bromo-2',4'-dichloroacetophenone
2-Bromo-2',4'-difluoroacetophenone