tryptamine

Suppliers

Names

[ CAS No. ]:
61-54-1

[ Name ]:
tryptamine

[Synonym ]:
2-(1H-Indol-3-yl)ethylamine
Tryptamine
1H-Indole-3-ethanamine
2-indol-3-yl-ethylamine
Indole-ethylamine
L-TRYPTAMINE
EINECS 200-510-5
2-Indol-3-yl-aethylamin
Tryptamin
3-Indoleethanamine
2-(1H-Indol-3-yl)ethanamine
MFCD00005661
TRYPTAMINE(P)
T56 BMJ D2Z
[2-(1H-indol-3-yl)-ethyl]amine
TRIPTAMINE
(1H-indol-3-yl)ethanamine
2-indol-3-ylethylamine

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
378.8±0.0 °C at 760 mmHg

[ Melting Point ]:
113-116 °C(lit.)

[ Molecular Formula ]:
C₁₀H₁₂N₂

[ Molecular Weight ]:
160.216

[ Flash Point ]:
187.7±8.1 °C

[ Exact Mass ]:
160.100052

[ PSA ]:
41.81000

[ LogP ]:
1.38

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.669

[ Water Solubility ]:
negligible

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL4020000

CHEMICAL NAME :: Indole, 3-(2-aminoethyl)-

CAS REGISTRY NUMBER :: 61-54-1

BEILSTEIN REFERENCE NO. :: 0125513

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C10-H12-N2

MOLECULAR WEIGHT :: 160.24

WISWESSER LINE NOTATION :: T56 BMJ D2Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 223 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 66,1692,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,453,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae. (Warsaw, Poland) V.18-24, 1966-72. For publisher information, see PJPPAA. Volume(issue)/page/year: 22,313,1970

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
20/21/22-36/37/38-41-37/38-22

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
NL4020000

[ HS Code ]:
29339990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

3-(2-nitroethyl)indole
Boc-Tryptamine
3-Indoleacetonitrile
tert-butyl 4-(2-aminophenyl)-2,3-dihydro-1H-pyrrole-1-carboxylate
(2-INDOL-3-YLETHYL)((4-METHYLPHENYL)SULFONYL)AMINE
L(-)-Tryptophan
indole-3-glyoxylamide
(3-Indolyl)acetaldehyd-dimethylhydrazon
Indole

DownStream

1-(trifluoromethyl)-9H-pyrido[3,4-b]indole
5,5-diethyl-6-[2-(1H-indol-3-yl)ethylamino]pyrimidine-2,4-dione
2,2,2-trifluoro-N-[2-(1-methylindol-3-yl)ethyl]acetamide
5-Hydroxytryptamine
Dimethyltryptamine
5-Methoxy-3-indoleaceate
2-(1-BENZYL-1H-INDOL-3-YL)-ETHYLAMINE
1-phenyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
1-Phenyl-9H-?carboline

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Use of Commercial Dry Yeast Products Rich in Mannoproteins for White and Rosé Sparkling Wine Elaboration.

J. Agric. Food Chem. 63 , 5670-81, (2015)

In sparkling wines, mannoproteins released during yeast autolysis largely affect their final quality. This process is very slow and may take several months. The aim of this work was to study the effec...

Enantioselective formal synthesis of ent-rhynchophylline and ent-isorhynchophylline.

Chem. Commun. (Camb.) 49(19) , 1954-6, (2013)

Starting from (S)-tryptophanol, a formal synthesis of ent-rhynchophylline and ent-isorhynchophylline, involving stereoselective cyclocondensation, spirocyclization, and alkylation reactions, and the f...

A separation of tyramine on a 2-(4-methoxyphenyl)ethylamine imprinted polymer: an answer from theoretical and experimental studies.

Talanta 129 , 155-64, (2014)

A 2-(4-methoxyphenyl)ethylamine imprinted polymer (MIP) was successfully applied for the selective separation of tyramine. A computational analysis was used to predict the affinity of the polymer matr...