Sulthiame

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Names

[ CAS No. ]:
61-56-3

[ Name ]:
Sulthiame

[Synonym ]:
Sulthiamine
Sultiamum
Trolone
SULTHIAME
sultiame
Conadil
Riker 594
Ospolot
Contravul
Sulphenyltame

Chemical & Physical Properties

[ Density]:
1.472g/cm3

[ Boiling Point ]:
520.2ºC at 760 mmHg

[ Molecular Formula ]:
C10H14N2O4S2

[ Molecular Weight ]:
290.35900

[ Flash Point ]:
268.4ºC

[ Exact Mass ]:
290.03900

[ PSA ]:
114.30000

[ LogP ]:
3.19090

[ Index of Refraction ]:
1.609

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DB3150000
CHEMICAL NAME :
Benzenesulfonamide, p-(tetrahydro-2H-1,2-thiazin-2-yl)-, dioxide
CAS REGISTRY NUMBER :
61-56-3
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C10-H14-N2-O4-S2
MOLECULAR WEIGHT :
290.38
WISWESSER LINE NOTATION :
T6NSWTJ AR DSZW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ATXKA8 Archiv fuer Toxikologie. (Berlin, Fed. Rep. Ger.) V.15-31, 1954-74. For publisher information, see ARTODN. Volume(issue)/page/year: 25,229,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,383,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1650 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,306,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4852 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,306,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1668 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,306,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,306,1972

Safety Information

[ HS Code ]:
2935009090

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%


Related Compounds

  • Sulthiame-d4
  • 5,11-Dihydro-5-phenyl-11-(4-phenyl-2-quinazolinyl)indolo[3,2-b]carbazole
  • N-Methyl-1-(1-methylcyclohexyl)methanesulfonamide
  • 1-(Benzo[d]thiazol-2-yl)-1-(dec-7-ynyl)hydrazine
  • (2S)-5,5-difluoro-4,4-dimethyl-2-(phenylmethoxycarbonylamino)pentanoic acid
  • (6-Bromo-1-methyl-1h-benzimidazol-2-yl)cyclopropylmethanone
  • 1-(8-Chloro-4-hydroxy-2-phenylquinolin-3-yl)ethanone
  • 3-(Benzyloxy)-5-chloro-2-methylpyrazine
  • (2S)-3-(3,3-Difluorocyclobutyl)-2-methylpropanoic acid
  • Potassium trifluoro(4-fluorophenethyl)borate
  • Ethyl 6-chloroimidazo[1,2-a]pyrazine-2-carboxylate
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