Methyl 2-​furoate

Suppliers

Names

[ CAS No. ]:
611-13-2

[ Name ]:
Methyl 2-​furoate

[Synonym ]:
Methyl 2-furoate
2-Furancarboxylic acid, methyl ester
methyl furan-2-carboxylate
Methyl furoate
Furancarboxylic acid, methyl ester
EINECS 210-254-6
MFCD00003236
Methyl furancarboxylate
Methyl 2-​furoate

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
181.3±0.0 °C at 760 mmHg

[ Melting Point ]:
36ºC

[ Molecular Formula ]:
C6H6O3

[ Molecular Weight ]:
126.110

[ Flash Point ]:
73.3±0.0 °C

[ Exact Mass ]:
126.031693

[ PSA ]:
39.44000

[ LogP ]:
0.99

[ Vapour Pressure ]:
0.9±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.463

[ Water Solubility ]:
slightly soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LV1950000
CHEMICAL NAME :
2-Furoic acid, methyl ester
CAS REGISTRY NUMBER :
611-13-2
BEILSTEIN REFERENCE NO. :
0111110
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C6-H6-O3
MOLECULAR WEIGHT :
126.12
WISWESSER LINE NOTATION :
T5OJ BVO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,869,1979 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
75 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 58,174,1936
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,869,1979

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H312-H315-H319-H335

[ Precautionary Statements ]:
P261-P280-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R21/22;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39

[ RIDADR ]:
UN 2810 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
LV1950000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29321900

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Bromofuran
  • carbon monoxide
  • Furfural
  • Potassium methoxide
  • Furfuryl alcohol
  • Methanol
  • Furan-2-carboxylic acid
  • Velcorin
  • 2-Furoyl chloride
  • Furan

DownStream

  • 2-Furancarboxamide,N-(2-hydroxyethyl)-(9CI)
  • 1-(2-furoyl)piperazine
  • Dimethyl furan-2,5-dicarboxylate
  • Methyl 3-(2-furyl)-3-oxopropanoate
  • 2-furoylacetonitrile
  • Ethyl 3-(2-furyl)-3-oxopropanoate
  • 5-(TERT-BUTYL)FURAN-2-CARBOXYLIC ACID
  • Methyl 5-(hydroxymethyl)-2-furoate
  • 1,1-bis-(2'-methoxyfuroyl-5'-methyleneoxy)methane
  • 5-formyloximethyl-furan-2-carboxylic acid methyl ester

Customs

[ HS Code ]: 2932190090

[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Enantioselective synthesis of furo[2,3-b]furans, a spongiane diterpenoid substructure.

Org. Lett. 7(24) , 5353-6, (2005)

[structure: see text] A short and enantioselective synthesis of cis-fused 5-oxofuro[2,3-b]furans, being found in many spongiane diterpenoid natural products, is reported starting from inexpensive meth...

Asymmetric synthesis of both enantiomers of arteludovicinolide A.

Org. Lett. 15(13) , 3420-3, (2013)

The first total synthesis of either enantiomer of Arteludovicinolide A and their biological evaluation is reported, featuring a new strategy for the asymmetric construction of γ-butyrolactones with st...


More Articles


Related Compounds

  • Methyl 2-furoate
  • METHYL3-METHYL-2-FUROATE
  • methyl 5-methyl-2-furoate
  • METHYL 5-[(PHENYLSULFONYL)METHYL]-2-FUROATE
  • METHYL 5-[(BENZYLAMINO)METHYL]-2-FUROATE HYDROCHLORIDE
  • Methyl 5-[(diethylamino)methyl]-2-furoate
  • 5-Amino-2-(perfluorophenyl)isonicotinic acid
  • 2,4(3H,5H)-Pyrimidinedione, 5,5-diethyl-6-((4-methylphenyl)amino)-
  • 5-Amino-6-(perfluorophenyl)nicotinic acid
  • 2-Methoxy-3,5-bis(trifluoromethyl)pyridine
  • 4-Thia-2,6-diazabicyclo(3.2.0)hept-2-ene-6-acetic acid, alpha-(1-methylethenyl)-7-oxo-3-(phenylmethyl)-, (4-nitrophenyl)methyl ester, (alphaR,1R,5R)-
  • CID 131637267
  • Nitrofurazone-13c,15n3
  • 4-Fluoro-3-(tetrahydro-2H-pyran-3-yl)-1H-indole
  • Ethyl 3-fluoro-4-(trifluoromethyl)picolinate
  • 4-Pyridineacetic acid, 5-fluoro-2-methyl-, ethyl ester