o-Chlorobenzylchloride

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Names

[ CAS No. ]:
611-19-8

[ Name ]:
o-Chlorobenzylchloride

[Synonym ]:
Ortho-α-dichlorotoluene
Benzene, 1-chloro-2- (chloromethyl)-
2-chloromethylchlorobenzene
1-Chloro-2-(chloromethyl)benzene
,2-Dichlorotoluene
2-chloro-benzyl chloride
Toluene, o,α-dichloro-
α,o-Dichlorotoluene
A,O-DICHLOROTOLUENE
2-Chlorobenzyl chloride
OCBC
EINECS 210-258-8
o-Chlorobenzylchloride
2-CHLORO-1-CHLOROMETHYLBENZENE
Benzene, 1-chloro-2-(chloromethyl)-
MFCD00000893
2-Chlorobenzyl chlor
o,α-Dichlorotoluene
α,2-Dichlorotoluene
o-Chlorobenzyl chloride
o-benzyl chloride

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
213.7±15.0 °C at 760 mmHg

[ Melting Point ]:
-13 °C

[ Molecular Formula ]:
C7H6Cl2

[ Molecular Weight ]:
161.029

[ Flash Point ]:
82.2±0.0 °C

[ Exact Mass ]:
159.984650

[ LogP ]:
3.08

[ Vapour density ]:
5.5 (vs air)

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.547

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CZ0195000
CHEMICAL NAME :
Benzene, 1-chloro-2-(chloromethyl)-
CAS REGISTRY NUMBER :
611-19-8
BEILSTEIN REFERENCE NO. :
0471700
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C7-H6-Cl2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1140 mg/m3/1H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0990-1020
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
430 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0990-1020 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84023 No. of Facilities: 5 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 20 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84023 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 4354 (estimated) No. of Female Employees: 729 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H317-H330

[ Precautionary Statements ]:
P260-P280-P284-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R20/21/22;R34;R50/53

[ Safety Phrases ]:
S26-S36/37/39-S45-S29

[ RIDADR ]:
UN 2235 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
CZ0195000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29036990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Chlorotoluene
  • 2-chlorobenzyl hypochlorothioite
  • 2-Chlorobenzaldehyde
  • 2-Chlorobenzyl alcohol
  • o-Toluenesulfonyl chloride
  • Benzyl chloride
  • Sulfuryl chloride
  • 2-Bromotoluene
  • Benzoyl peroxide
  • molecular iodine

DownStream

  • 2-CHLOROBENZYLZINC CHLORIDE
  • Ticlopidine
  • IMINOSTILBENE
  • Ethanamine,2-[[(2-chlorophenyl)methyl]thio]-
  • 2-(2-CHLORO-BENZYLOXY)-BENZOIC ACID
  • orbencarb
  • 1-benzylimidazole
  • 2-(2-chlorobenzyloxy)benzaldehyde
  • (2-Chlorophenyl)acetaldehyde
  • Ticlopidine Hydrochloride

Customs

[ HS Code ]: 29036990

Articles

Computer-based bioassay for evaluation of sensory irritation of airborne chemicals and its limit of detection.

Arch. Toxicol. 72(5) , 277-82, (1998)

We expanded a previously described rule-based computerized method to recognize the sensory irritating effect of airborne chemicals. Using 2-chlorobenzylchloride (CBC) as a sensory irritant, characteri...

Computer assisted recognition and quantitation of the effects of airborne chemicals acting at different areas of the respiratory tract in mice.

Arch. Toxicol. 68(8) , 490-9, (1994)

The pattern and timing of a normal breath in unanesthetized mice was analyzed from measurement of inspiratory and expiratory airflows (VI and VE). Airflow was measured via a differential pressure tran...

Sterol-content lowering action of o-chlorobenzylchloride in yeast.

J. Biochem. 88(1) , 97-102, (1980)

o-Chlorobenzylchloride, a simple aromatic halogen compound, was found to inhibit the growth of Saccharomyces cerevisiae and to lower the contents of sterols and fatty acids. The growth inhibition was ...


More Articles

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