2-Cyanophenol

Names

[ CAS No. ]:
611-20-1

[ Name ]:
2-Cyanophenol

[Synonym ]:
2-Cyanophenol
Benzonitrile, o-hydroxy-
QR BCN
EINECS 210-259-3
Benzonitrile, 2-hydroxy-
2-Hydroxybenzonitrile
o-Cyanophenol
Salicylonitrile
MFCD00002145

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
273.1±0.0 °C at 760 mmHg

[ Melting Point ]:
92-95 °C(lit.)

[ Molecular Formula ]:
C₇H₅NO

[ Molecular Weight ]:
119.12

[ Flash Point ]:
109.6±22.6 °C

[ Exact Mass ]:
119.037117

[ PSA ]:
44.02000

[ LogP ]:
1.61

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.591

[ Stability ]:
Stable. Incompatible with strong oxidizing agents, strong bases.

[ Water Solubility ]:
soluble

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36-S45

[ RIDADR ]:
3276

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29269095

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Salicylaldehyde
2-Bromobenzonitrile
2-Chlorophenol
zinc,dicyanide
2-Methylbenzyl Alcohol
2-TERT-BUTOXY-BENZONITRILE
Salicylamide
Methyl salicylate

DownStream

5-Bromo-2-hydroxybenzonitrile
3-bromo-2-hydroxybenzonitrile
3,5-dibromo-2-hydroxybenzonitrile
Methyl 3-amino-2-benzo[b]furancarboxylate
2-(((2-hydroxybenzyl)amino)methyl)phenol
1-(3,6-DIBROMO-CARBAZOL-9-YL)-3-PYRROLIDIN-1-YL-PROPAN-2-OL
Ethyl 3-amino-1-benzofuran-2-carboxylate
3-Amino-1-benzofuran-2-carboxamide
Benzooxazol-2-ylamine
Ethyl 2-(2-cyanophenoxy)acetate ,96

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).

J. Med. Chem. 48 , 3269-79, (2005)

Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm...

Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.

J. Med. Chem. 48 , 7234-42, (2005)

In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspas...

Enantioselective Cu-catalyzed 1, 4-addition of Me₃Al to a 4, 4-disubstituted cyclohexa-2, 5-dienone. Takemoto Y, et al.

Tetrahedron 52(45) , 14177-14188, (1996)