Quinolin-5-amine
Suppliers
Names
[ CAS No. ]:
611-34-7
[ Name ]:
Quinolin-5-amine
[Synonym ]:
quinolin-5-amine
5-Quinolinamine
5-Quinolinamine (9CI)
5-amino-quinoline
5-amino-quinolin
Chinolin-5-amin
EINECS 210-266-1
5-Aminoquinoline
Quinolin-5-ylamine
5-Quinolylamine
MFCD00006797
5-aminoqionoline
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
310.0±0.0 °C at 760 mmHg
[ Melting Point ]:
106-109 °C(lit.)
[ Molecular Formula ]:
C9H8N2
[ Molecular Weight ]:
144.17
[ Flash Point ]:
171.5±8.1 °C
[ Exact Mass ]:
144.068741
[ PSA ]:
38.91000
[ LogP ]:
0.92
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.708
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VA9625000
- CHEMICAL NAME :
- Quinoline, 5-amino-
- CAS REGISTRY NUMBER :
- 611-34-7
- BEILSTEIN REFERENCE NO. :
- 0114479
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C9-H8-N2
- MOLECULAR WEIGHT :
- 144.19
- WISWESSER LINE NOTATION :
- T66 BNJ GZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex)
MUTATION DATA
- TYPE OF TEST :
- DNA repair
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 16 ug/well
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,429,1981
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
VA9625000
[ Packaging Group ]:
III
[ HS Code ]:
2933499090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933499090
[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Biochem. Pharmacol. 48(8) , 1593-604, (1994)
The 4-alkylamino-5-nitroquinolines (5NQs) are a new series of bioreductive drugs that exhibit varying degrees of selective toxicity (up to 60-fold) under hypoxic conditions in cell culture. This study...
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 74(5) , 1215-23, (2009)
The Fourier transform infrared (FTIR) and FT-Raman spectra of 5-aminoquinoline (5AQ) have been recorded in the range 4000-400 and 3500-100 cm(-1), respectively. The complete vibrational assignment and...
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 79(3) , 412-7, (2011)
Graphical abstract Photophysical/photochemical properties of 5-aminoquinoline (5AQ) have been investigated. In aprotic solvents, the spectra depend on the polarity. However, in protic solvents both th...