4-quinolone

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Names

[ CAS No. ]:
611-36-9

[ Name ]:
4-quinolone

[Synonym ]:
4-Quinolinol
Chinolin-4-ol
p-hydroxyquinoline
4-quinolone
4(1H)-QUINOLINONE
Chinolin-4(1H)-on
Quinolin-4(1H)-one
quinolin-4-one
1,4-Dihydroquinoline-4-one
HYDROXYQUINOLINE,4
4-hydroxyquinoline acid
KYNURINE
4-Hydroxyquinoline
4-oxo-1,4-dihydroquinoline
4-hydroxy-quinolin
EINECS 210-268-2
quinolin-4-ol
quinoline-4-ol
MFCD00006777

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
313.0±15.0 °C at 760 mmHg

[ Melting Point ]:
200-202 °C(lit.)

[ Molecular Formula ]:
C9H7NO

[ Molecular Weight ]:
145.158

[ Flash Point ]:
143.1±20.4 °C

[ Exact Mass ]:
145.052765

[ PSA ]:
33.12000

[ LogP ]:
2.45

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.691

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VC4070000
CHEMICAL NAME :
4-Quinolinol
CAS REGISTRY NUMBER :
611-36-9
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C9-H7-N-O
MOLECULAR WEIGHT :
145.17

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
VC4070000

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 7-Chloro-2,3-dihydro-4-quinolone
  • 5-(ANILINOMETHYLENE)-2,2-DIMETHYL-1,3-DIOXANE-4,6-DIONE
  • Meldrumic acid
  • 4-Chloroquinoline
  • quinoline 1-oxide
  • Dichloroacetyl chloride
  • 2-(6-Methoxynaphthalen-2-yl)propanoic acid
  • DL-Tryptophan
  • Methanol

DownStream

  • 4-Chloro-3-nitroquinoline
  • 4-Methoxyquinoline
  • 1-methylquinolin-4-one
  • 2-ethyl-1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine
  • 2-quinolin-4-yloxyacetic acid
  • N-[1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-yl]benzamide
  • 4-quinolin-4-ylsulfanylquinoline
  • 4-amino-3-nitroquinoline
  • 3-Nitro-4-quinolinol
  • 4-Chloro-8-nitroquinoline

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synergistic antidepressant-like effect of ferulic acid in combination with piperine: involvement of monoaminergic system.

Metab. Brain Dis. 30 , 1505-14, (2015)

The lifetime prevalence rate for major depressive disorder (MDD) is approximately 17 % for most developed countries around the world. Dietary polyphenols are currently used as an adjuvant therapy to a...

Evolution from a natural flavones nucleus to obtain 2-(4-Propoxyphenyl)quinoline derivatives as potent inhibitors of the S. aureus NorA efflux pump.

J. Med. Chem. 54 , 5722-36, (2011)

Overexpression of efflux pumps is an important mechanism by which bacteria evade the effects of substrate antimicrobial agents. Inhibition of such pumps is a promising strategy to circumvent this resi...

Antioxidant properties of 4-quinolones and structurally related flavones.

Bioorg. Med. Chem. 20 , 809-18, (2012)

Neurodegenerative disorders are frequently associated with increased oxidative damage to the brain as a result of free radicals produced by cellular respiration. The onset and progression of neurodege...


More Articles

Related Compounds

  • 4-quinolone
  • 4-quinolone
  • 3-cyano-4-quinolone
  • 2-nonyl-4-quinolone
  • 6-cyano-4-quinolone
  • 6-nitro-4-quinolone
  • 1-(cis-Hexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl)propan-1-one
  • 1-(cis-Hexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl)-3-methylbutan-1-one
  • (cis-Hexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl)(p-tolyl)methanone
  • (3aS,6aS)-1-(2-methylbenzoyl)-octahydropyrrolo[2,3-c]pyrrole
  • (3aS,6aS)-1-(3-fluorobenzoyl)-octahydropyrrolo[2,3-c]pyrrole
  • Rel-((3aS,6aS)-hexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl)(3-methylfuran-2-yl)methanone
  • (cis-Hexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl)(5-methylisoxazol-4-yl)methanone
  • 5-[(3aS,6aS)-octahydropyrrolo[2,3-c]pyrrole-1-carbonyl]-2-methylpyridine
  • (cis-Hexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl)(5-methylpyrazin-2-yl)methanone
  • 1-((3aS,6aS)-Hexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl)-3,3-dimethylbutan-1-one
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