5-Ethynyl-2'-deoxyuridine

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Names

[ CAS No. ]:
61135-33-9

[ Name ]:
5-Ethynyl-2'-deoxyuridine

[Synonym ]:
5-ethynyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
5-Ethynyl-2'-deoxyuridine

Chemical & Physical Properties

[ Density]:
1.55g/cm3

[ Melting Point ]:
199 °C

[ Molecular Formula ]:
C11H12N2O5

[ Molecular Weight ]:
252.22300

[ Exact Mass ]:
252.07500

[ PSA ]:
104.55000

[ Index of Refraction ]:
1.644

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YU7510000
CHEMICAL NAME :
Uridine, 2'-deoxy-5-ethynyl-
CAS REGISTRY NUMBER :
61135-33-9
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H12-N2-O5
MOLECULAR WEIGHT :
252.25

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lung
DOSE/DURATION :
500 ug/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 117,317,1983

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H340-H361

[ Precautionary Statements ]:
P201-P281-P308 + P313

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • idoxuridine
  • 5-Ethynyl-3',5'-di-O-p-toluyl-2'-deoxyuridine
  • 1-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-5-iodouracil
  • 3',5'-di-O-trifluoroacetyl-5-iodo-2'-deoxyuridine
  • TMS-acetylene
  • 5-(1-chlorovinyl)-2'-deoxy-3',5'-di-O-(p-toluoyl)uridine
  • 5-Hydroxy-2'-deoxyuridine
  • 5-(Trifluoromethanesulfonyloxy)-2'-deoxyuridine

DownStream

  • Edoxudine
  • 2-[[5-(5-ethenyl-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]acetic acid
  • 5-vinyl-2'-deoxyuridine
  • Uridine,5-acetyl-2'-deoxy- (9CI)
  • 5-[2-(4-tert-butylphenyl)ethynyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

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Related Compounds

  • 5-ethynyl-2'-deoxyuridine
  • C-5-ethynyl-2'-deoxyuridine
  • 5-ethynyl-2'-deoxyuridine-5'-triphosphate
  • 5-Ethynyl-2'-deoxyuridine5'-triphosphatesodiumsalt
  • 5'-O-(4,4'-dimethoxytrityl)-5-ethynyl-2'-deoxyuridine
  • 5-Ethynyl-3',5'-di-O-p-toluyl-2'-deoxyuridine
  • N-(2,2-Diethoxyethyl)-4-(methylthio)benzenamine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 7,9-Dioxa-2,3-dithiaspiro[4.5]decan-8-one
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine