6-Chloroquinoline

Names

[ CAS No. ]:
612-57-7

[ Name ]:
6-Chloroquinoline

[Synonym ]:
6-Chloroquinoline
EINECS 210-314-1
Quinoline,6-chloro
6-chloro-quinoline
MFCD00024024
6-Chlor-chinolin
Quinoline, 6-chloro-
6-chloroquiniline

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
263.0±0.0 °C at 760 mmHg

[ Melting Point ]:
41-43 °C(lit.)

[ Molecular Formula ]:
C₉H₆ClN

[ Molecular Weight ]:
163.604

[ Flash Point ]:
145.2±5.4 °C

[ Exact Mass ]:
163.018875

[ PSA ]:
12.89000

[ LogP ]:
2.73

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.652

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-chloro-N-prop-2-ynylaniline
3-[bis(3-hydroxypropyl)amino]propan-1-ol
4-Chloronitrobenzene
6-quinolinyl trifluoromethanesulfonate
3-Aminopropan-1-ol
6-Chloro-1,2,3,4-tetrahydroquinoline
4-Chloroaniline
1,3-Propanediol
5-[(4-chloro-2-formylphenylamino)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione
6-chloro-1-(methylsulfonyl)-1,2-dihydroquinoline

DownStream

6-Quinolineboronic acid pinacol ester
5-Amino-6-chloroquinoline
6-Chloro-8-quinolinamine
6-Hydroxyquinoline
6-Aminoquinoline
6-Chloro-1,2,3,4-tetrahydroquinoline
1,2,3,4-Tetrahydroquinoline
leucoline
4,6-Dichloroquinoline
Methyl quinoline-6-carboxylate

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Palladium charcoal-catalyzed Suzuki-Miyaura coupling to obtain arylpyridines and arylquinolines.

J. Org. Chem. 68(24) , 9412-5, (2003)

A phosphine ligand, such as PPh3 or 2-(dicyclohexylphosphino)biphenyl, is essential for the Pd/C-catalyzed Suzuki-Miyaura coupling of halopyridines and haloquinolines, although it has been reported th...

J. Org. Chem. 55 , 5230, (1990)

Polarographic reduction of 6-chloroquinoline in dimethylformamide. Fujinaga T and Takaoka K.

J. Electroanal. Chem. Interfac. Electrochem. 16(1) , 99-110, (1968)