AZD1080

Suppliers

Names

[ CAS No. ]:
612487-72-6

[ Name ]:
AZD1080

[Synonym ]:
1H-Indole-5-carbonitrile, 2-hydroxy-3-[5-(4-morpholinylmethyl)-2-pyridinyl]-
2-Hydroxy-3-[5-(4-morpholinylmethyl)-2-pyridinyl]-1H-indole-5-carbonitrile
2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]-1H-indole-5-carbonitrile
1H-INDOLE-5-CARBONITRILE,2-HYDROXY-3-[5-(4-MORPHOLINYLMETHYL)-2-PYRIDINYL]
Kinome_2945
AZD1080

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
594.0±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H18N4O2

[ Molecular Weight ]:
334.372

[ Flash Point ]:
313.0±30.1 °C

[ Exact Mass ]:
334.142975

[ PSA ]:
85.17000

[ LogP ]:
1.36

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.716

[ Storage condition ]:
-20°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-bromo-3-[5-(morpholin-4-ylmethyl)-1H-pyridin-2-ylidene]-1H-indol-2-one
  • zinc,dicyanide
  • 1,2-dihydroxy-3-(5-morpholin-4-ylmethyl-pyridin-2-yl)-1H-indole-5-carbonitrile
  • (2-amino-5-cyano-phenyl)-(5-morpholin-4-ylmethyl-pyridin-2-yl)-acetic acid ethyl ester
  • 4-((6-Chloropyridin-3-yl)methyl)morpholine

DownStream

Related Compounds

  • 2-(4-amino-2H-1,2,3-triazol-2-yl)-N-cyclopentylacetamide
  • 2-(2,2,5,5-tetramethyloxolan-3-yl)-2H-1,2,3-triazol-4-amine
  • 2-(4-amino-2H-1,2,3-triazol-2-yl)-N-(2-methylbutan-2-yl)acetamide
  • 1-(4-amino-2H-1,2,3-triazol-2-yl)-3-[methyl(propan-2-yl)amino]propan-2-ol
  • 2-({imidazo[2,1-b][1,3]thiazol-6-yl}methyl)-2H-1,2,3-triazol-4-amine
  • 1-[(2-cyclopropyl-1,3-thiazol-4-yl)methyl]-1H-1,2,3-triazol-4-amine
  • 1-[(4-methyloxan-4-yl)methyl]-1H-1,2,3-triazol-4-amine
  • ethyl[4-(4-methanesulfonyl-1H-pyrazol-1-yl)butan-2-yl]amine
  • 1-(4-methanesulfonyl-1H-pyrazol-1-yl)-3,3-dimethylbutan-2-amine
  • 2-[2-(4-methanesulfonyl-1H-pyrazol-1-yl)ethyl]-N-methylcyclopentan-1-amine
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