N,N'-DIACETYLBENZIDINE
Suppliers
Names
[ CAS No. ]:
613-35-4
[ Name ]:
N,N'-DIACETYLBENZIDINE
[Synonym ]:
Acetamide, N,N'-[1,1'-biphenyl]-4,4'-diylbis-
N-[4'-(acetylamino)[1,1'-biphenyl]-4-yl]acetamide
N-[4-(4-acetamidophenyl)phenyl]acetamide
EINECS 210-338-2
N,N'-biphenyl-4,4'-diyldiacetamide
N,N'-DIACETYLBENZIDINE
N,N'-4,4'-Biphenyldiyldiacetamide
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
562.9±43.0 °C at 760 mmHg
[ Melting Point ]:
328.3ºC
[ Molecular Formula ]:
C16H16N2O2
[ Molecular Weight ]:
268.310
[ Flash Point ]:
224.7±28.3 °C
[ Exact Mass ]:
268.121185
[ PSA ]:
58.20000
[ LogP ]:
2.31
[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C
[ Index of Refraction ]:
1.638
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DT2800000
- CHEMICAL NAME :
- 4',4'''-Biacetanilide
- CAS REGISTRY NUMBER :
- 613-35-4
- BEILSTEIN REFERENCE NO. :
- 2217711
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C16-H16-N2-O2
- MOLECULAR WEIGHT :
- 268.34
- WISWESSER LINE NOTATION :
- 1VMR DR DMV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6300 mg/kg/35W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 64 mg/kg/4W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Endocrine - tumors Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Liver - hepatitis (hepatocellular necrosis), zonal Kidney, Ureter, Bladder - changes in both tubules and glomeruli
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4350 mg/kg/39W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Liver - hepatitis (hepatocellular necrosis), zonal Kidney, Ureter, Bladder - changes in both tubules and glomeruli
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 389,3,1997 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,293,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,293,1978 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FRANCE;Carcinogen JAN 1993
Safety Information
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
20/21/22
[ Safety Phrases ]:
S22;S26
[ RTECS ]:
DT2800000
[ HS Code ]:
2924299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%