2-Amino-1-phenylethanone
Suppliers
Names
[ CAS No. ]:
613-89-8
[ Name ]:
2-Amino-1-phenylethanone
[Synonym ]:
2-Acetylaniline
2-aminoacetophenone hydrochloride
a-Aminoacetophenone
Ethanone, 2-amino-1-phenyl-
ACETOPHENONE,2-AMINO
Ethanone, 1-(2-aminophenyl)-
w-Aminoacetophenone
2'-Amonioacetophenone
Phenacylamine
1-(2-Aminophenyl)ethanone
phenylcarbonylmethylamine
2-Amino-1-phenylethanone
o-Acetylaniline
2-Amino-1-phenylethan-1-one
o-Aminoacetophenone
2`-Aminoacetophenone
2-Aminoecetophenone
2-amino-1-phenyl-ethanone
2-amino-acetophenone
ortho-Aminoacetophenone
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
247.3±23.0 °C at 760 mmHg
[ Molecular Formula ]:
C8H9NO
[ Molecular Weight ]:
135.163
[ Flash Point ]:
103.4±22.6 °C
[ Exact Mass ]:
135.068420
[ PSA ]:
43.09000
[ LogP ]:
0.81
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.552
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AM5775000
- CHEMICAL NAME :
- Acetophenone, 2-amino-
- CAS REGISTRY NUMBER :
- 613-89-8
- BEILSTEIN REFERENCE NO. :
- 0507952
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C8-H9-N-O
- MOLECULAR WEIGHT :
- 135.18
- WISWESSER LINE NOTATION :
- ZR BV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2000 mg/kg/7W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Blood - leukemia
- REFERENCE :
- PGPKA8 Problemy Gematologii i Perelivaniia Krovi. Problems of Hematology and Blood Transfusion. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1956- Volume(issue)/page/year: 14,12,1969
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1480 mg/kg/13W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Liver - angiosarcoma Reproductive - Tumorigenic effects - uterine tumors
- REFERENCE :
- BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 84,1156,1977
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 1600 mg/kg/10W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Endocrine - adrenal cortex tumors Endocrine - thyroid tumors
- REFERENCE :
- VOONAW Voprosy Onkologii. Problems of Oncology. For English translation, see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1928-37; V.1- 1955- Volume(issue)/page/year: 25(6),81,1979
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1600 mg/kg/8W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors
- REFERENCE :
- VOONAW Voprosy Onkologii. Problems of Oncology. For English translation, see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1928-37; V.1- 1955- Volume(issue)/page/year: 22(6),47,1976
Safety Information
[ HS Code ]:
2922399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922399090
[ Summary ]:
2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%