trans-1-(2-Chloroethyl)-3-(4-hydroxymethylcyclohexyl)-1-nitrosourea formate
Suppliers
Names
[ CAS No. ]:
61367-11-1
[ Name ]:
trans-1-(2-Chloroethyl)-3-(4-hydroxymethylcyclohexyl)-1-nitrosourea formate
[Synonym ]:
trans-1-(2-Chloroethyl)-3-(4-hydroxymethylcyclohexyl)-1-nitrosourea formate
Urea,1-(2-chloroethyl)-3-(4-hydroxymethylcyclohexyl)-1-nitroso-,formate,(E)
(4-{[(2-chloroethyl)(nitroso)carbamoyl]amino}cyclohexyl)methyl formate
Chemical & Physical Properties
[ Density]:
1.39g/cm3
[ Molecular Formula ]:
C11H18ClN3O4
[ Molecular Weight ]:
291.73100
[ Exact Mass ]:
291.09900
[ PSA ]:
88.07000
[ LogP ]:
2.67680
[ Index of Refraction ]:
1.577
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YS4986300
- CHEMICAL NAME :
- Urea, 1-(2-chloroethyl)-3-(4-hydroxymethylcyclohexyl)-1-nit roso-, formate, (E)-
- CAS REGISTRY NUMBER :
- 61367-11-1
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C11-H18-Cl-N3-O4
- MOLECULAR WEIGHT :
- 291.77
- WISWESSER LINE NOTATION :
- L6TJ AMVNNO&2G D1OVH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD10 - Lethal Dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 22 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1095,1980