1-(2-Methylphenyl)thiourea

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Names

[ CAS No. ]:
614-78-8

[ Name ]:
1-(2-Methylphenyl)thiourea

[Synonym ]:
Thiourea, N-(2-methylphenyl)-
2-tolylthiourea
2-THIO-1-O-TOLYLUREA
1-(2-Methylphenyl)thiourea
2-thio-1-o-tolyl-ure
MFCD00041162
(2-methylphenyl)thiourea
EINECS 210-395-3
O-TOLYLTHIOUREA
1-o-Tolyl-2-thiourea
N-(o-Tolyl)thiourea
ortho-Tolylthiourea
o-methylphenyl thiourea
1-o-tolylthiocarbamide
thiourea,1-(2-tolyl)

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
275.5±33.0 °C at 760 mmHg

[ Melting Point ]:
149 °C

[ Molecular Formula ]:
C8H10N2S

[ Molecular Weight ]:
166.243

[ Flash Point ]:
120.4±25.4 °C

[ Exact Mass ]:
166.056473

[ PSA ]:
70.14000

[ LogP ]:
1.19

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.696

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YU2975000
CHEMICAL NAME :
Urea, 2-thio-1-o-tolyl-
CAS REGISTRY NUMBER :
614-78-8
LAST UPDATED :
199710
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C8-H10-N2-S
MOLECULAR WEIGHT :
166.26
WISWESSER LINE NOTATION :
SUYZMR B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,1,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0484 No. of Facilities: 76 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 292 (estimated)

Safety Information

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S22-S26-S36/37/39

[ RIDADR ]:
2811

[ RTECS ]:
YU2975000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2930909090

Synthetic Route

Precursor & DownStream

Precursor

  • o-Toluidine
  • Usaf k-1471
  • Sodium thiocyanate
  • o-Toluidine HCl
  • 2-Methylphenyl isothiocyanate
  • Potassium thiocyanate
  • bis(1-isothiocyanoethyl) ether

DownStream

  • (2-methylphenyl)cyanamide
  • N-[(2-methylphenyl)carbamothioyl]acetamide
  • Hydrazinecarbothioamide,N-(2-methylphenyl)-
  • amino-(2-methylphenyl)iminomethanesulfonic acid
  • 2-chloro-N-(4-methyl-1,3-benzothiazol-2-yl)acetamide
  • 3-(2-METHYLPHENYL)-2-THIOXOIMIDAZOLIDIN-4-ONE
  • (4,5-DICHLORO-6-OXO-1,6-DIHYDROPYRIDAZIN-1-YL)METHYL2-CHLORO-6-FLUOROBENZOATE
  • 4-Methylbenzo[d]thiazol-2-amine
  • 9-methyl-1,3-dinitro-10H-phenothiazine
  • 3-chloro-9-methyl-1-nitro-10H-phenothiazine

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds

  • 1-ethyl-1-(2-methylphenyl)thiourea
  • 3-[4-(1H-benzoimidazol-2-ylmethoxy)phenyl]-1-(2-methylphenyl)thiourea
  • 1-(2-methylphenyl)-3-(4-propoxyphenyl)thiourea
  • 1-(2-methylphenyl)-3-[(4-methylphenyl)-phenylmethyl]thiourea
  • 1-(2-methylphenyl)-3-(4-methylpyridin-2-yl)thiourea
  • 1-(2-methylphenyl)-3-(1,3-thiazol-2-yl)thiourea
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 5-Acetyl-3-nitrosalicylic acid
  • R-Toloxatone
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(2-methoxy-5-morpholin-4-ylsulfonylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde