alpha-Mangostin

Suppliers

Names

[ Name ]:
alpha-Mangostin

[Synonym ]:
1,3,6-Trihydroxy-7-methoxy-2,8-di(3-methyl-2-butenyl)xanthone
Mangostin
1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-enyl)xanthen-9-one
alpha-mangostin
EINECS 448-420-7
a-Mangostin
1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)-9H-xanthen-9-one
9H-Xanthen-9-one, 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methyl-2-buten-1-yl)-
1,3,6-Trihydroxy-7-méthoxy-2,8-bis(3-méthyl-2-butèn-1-yl)-9H-xanthén-9-one
1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
9H-Xanthen-9-one, 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)-
1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one
MFCD00135200

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
640.1±55.0 °C at 760 mmHg

[ Melting Point ]:
182ºC

[ Molecular Formula ]:
C₂₄H₂₆O₆

[ Molecular Weight ]:
410.460

[ Flash Point ]:
220.3±25.0 °C

[ Exact Mass ]:
410.172943

[ PSA ]:
100.13000

[ LogP ]:
5.45

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.624

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Hazard Codes ]:
T

[ Risk Phrases ]:
25

[ Safety Phrases ]:
45

[ RIDADR ]:
UN 2811 6.1 / PGIII

[ RTECS ]:
ZD6122420

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(4,6-dihydroxy-2-(methoxymethoxy)-3-(3-methylbut-2-en-1-yl)phenyl)(4,6-dihydroxy-3-methoxy-2-(3-methylbut-2-en-1-yl)phenyl)methanone
Phloroglucinol
2-[3-(1,3-benzodioxol-5-yl)-4-oxoquinazolin-2-yl]sulfanyl-N-ethyl-N-(3-methylphenyl)acetamide
2,4-bis(phenylmethoxy)-Benzaldehyde
1,3,5-tris(methoxymethoxy)benzene
b-Resorcylaldehyde
4,6-dihydroxy-2-(methoxymethoxy)-3-(3-methylbut-2-en-1-yl)benzaldehyde
1,3,5-tris(methoxymethoxy)-2-(3-methylbut-2-en-1-yl)benzene
2,4-bis(benzyloxy)-5-bromophenol
(((4-(allyloxy)-6-bromo-1,3-phenylene)bis(oxy))bis(methylene))dibenzene

DownStream

5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one
1-Isomangostin
3-Isomangostin hydrate
3,4-dihydro-5,9-dihydroxy-8-methoxy-7-(3-methoxy-3-methylbutyl)-2,2-dimethyl-2H,6H-pyrano-[3,2-b]xanthen-6-one
Isormangostin
4-methyl-3,6-di-O-methyl-α-mangostin
Fuscaxanthone C
3-Methyl-1-butanol
sulcatol

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Alpha-mangostin induces changes in glutathione levels associated with glutathione peroxidase activity in rat brain synaptosomes.

Nutr. Neurosci. 15(5) , 13-9, (2012)

In a previous report, we have characterized the antiperoxidative properties of alpha-mangostin in different toxic models tested in nerve tissue preparations.Here, the modulatory effects of this xantho...

A miniaturized flow-through cell to evaluate skin permeation of endoxifen.

Int. J. Pharm. 441(1-2) , 433-40, (2013)

Endoxifen, an anti-estrogenic agent, has been recently implicated in the use of breast cancer. Its physicochemical properties make it a good candidate for transdermal delivery. However, as an investig...

Neuroprotective effect of α-mangostin and curcumin against iodoacetate-induced cell death.

Nutr. Neurosci. 15(5) , 34-41, (2012)

Curcumin is a phenolic yellow curry pigment with anti-inflammatory and antioxidant activities and α-mangostin is a xanthone isolated from mangosteen fruit with antioxidant properties. Iodoacetate (IAA...

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