Quinacrine Dihydrochloride Dihydrate

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Names

[ CAS No. ]:
6151-30-0

[ Name ]:
Quinacrine Dihydrochloride Dihydrate

[Synonym ]:
Atebrin hydrochloride
Quinacrinehydrochlorid
MFCD00150069
866 R.P.
Chemiochin
Acrichine
mepacrinehydrochloridedihydrate
atabrinehydrochloridedihydrate
QuinacrineHCl
QUINACRINE,ATABRINE MEPACNINE
Mepacrine dihydrochloride
Chinacrin hydrochloride
hloride2h2-o
ochloride,dihydrate
Mecryl
Erion
Pentilen
mepacrinehcl
N-(6-Chloro-2-methoxy-9-acridinyl)-N,N-diethyl-1,4-pentanediamine dihydrochloride dihydrate
AtabrineMepacnine
QUINACRINE DIHYDROCHLORIDE
Palusan
1,4-Pentanediamine, N-(6-chloro-2-methoxy-9-acridinyl)-N,N-diethyl-, hydrochloride, hydrate (1:2:2)
Crinodora
Akrichin
Italchin
Metochin
Metoquine
Palacrin
69-05-6 {Anhydrous}
Acriquine
Malaricida

Chemical & Physical Properties

[ Boiling Point ]:
557.1ºC at 760 mmHg

[ Melting Point ]:
247 °C

[ Molecular Formula ]:
C23H36Cl3N3O3

[ Molecular Weight ]:
508.909

[ Exact Mass ]:
507.182220

[ PSA ]:
55.85000

[ LogP ]:
7.52080

[ Storage condition ]:
-20℃

[ Water Solubility ]:
2.8 g/100 mL

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AR7876000
CHEMICAL NAME :
Acridine, 6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2- methoxy-, dihydrochloride, dihydrate
CAS REGISTRY NUMBER :
6151-30-0
LAST UPDATED :
199112
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C23-H30-Cl-N3-O.2Cl-H.2H2-O
MOLECULAR WEIGHT :
507.96

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
37 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 44,225,1978 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intratesticular
DOSE :
4 mg/kg
SEX/DURATION :
male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 6,329,1972

Safety Information

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S37/39

Related Compounds

  • Quinacrine Dihydrochloride Dihydrate
  • Quinacrine (dihydrochloride)
  • Amodiaquin dihydrochloride dihydrate
  • (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,chloride,dihydrate,hydrochloride
  • 3-[4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazin-1-yl]propan-1-ol,dihydrochloride
  • Monodesethyl Quinacrine, Dihydrochloride
  • 3-(4-methoxyphenyl)-N-(2-(5-(3-methylbenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)propanamide
  • N-(2-(5-(3-methylbenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-5-nitrofuran-2-carboxamide
  • 2,4-difluoro-N-(2-(5-(3-methylbenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)benzamide
  • N-(2-(5-(4-methylbenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-2-propylpentanamide
  • N-(2-(5-(4-methylbenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)cyclopropanecarboxamide
  • N-(2-(5-(4-methylbenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)cyclohexanecarboxamide
  • 2-cyclopentyl-N-(2-(5-(4-methylbenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)acetamide
  • 2-ethoxy-N-(2-(5-(4-methylbenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)acetamide
  • 4-methyl-N-(2-(5-(4-methylbenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)benzamide
  • 4-(tert-butyl)-N-(2-(5-(4-methylbenzyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)benzamide
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