Phenylbutanolamine hydrochloride

Suppliers

Names

[ Name ]:
Phenylbutanolamine hydrochloride

[Synonym ]:
Nor-homoephedrine
1-hydroxy-1-phenylbutan-2-aminium chloride
Phenylbutanolamine hydrochloride
(1-hydroxy-1-phenylbutan-2-yl)azanium chloride
(1RS,2SR)-2-amino-1-phenyl-butan-1-ol,hydrochloride
(+/-)-(1R,2S)-2-amino-1-phenyl-1-butanol hydrochloride
(1RS,2SR)-2-Amino-1-phenyl-butan-1-ol,Hydrochlorid

Chemical & Physical Properties

[ Boiling Point ]:
302.4ºC at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₆ClNO

[ Molecular Weight ]:
201.69300

[ Flash Point ]:
136.7ºC

[ Exact Mass ]:
201.09200

[ PSA ]:
46.25000

[ LogP ]:
2.95960

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DN8050000

CHEMICAL NAME :: Benzyl alcohol, alpha-(1-aminopropyl)-, hydrochloride, (+-)-

CAS REGISTRY NUMBER :: 6170-27-0

LAST UPDATED :: 199509

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C10-H15-N-O.Cl-H

MOLECULAR WEIGHT :: 201.72

WISWESSER LINE NOTATION :: ZY2&YQR &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Vascular - BP elevation not characterized in autonomic section

REFERENCE :: JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 52,3317,1930

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 130 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: BANMAC Bulletin de l'Academie Nationale de Medicine (Paris). (Imprimeries Reunies de Chambray, 226, route d'Apremont, F-73490 La Ravoire, France) V.1- 1836- Volume(issue)/page/year: 98,101,1927