Epoprostenol sodium

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Names

[ Name ]:
Epoprostenol sodium

[Synonym ]:
(5Z)-5-{(3aR,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxyoct-1-én-1-yl]hexahydro-2H-cyclopenta[b]fur-2-ylidène}pentanoate de sodium
MFCD00135629
Natrium-(5Z)-5-{(3aR,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxyoct-1-en-1-yl]hexahydro-2H-cyclopenta[b]fur-2-yliden}pentanoat
PGI2
Flolan
Prostacyclin sodium
EINECS 234-237-8
Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, sodium salt, (9α,11α,13E,15S)- (1:1)
PG12-NA
(5Z,9a,11a,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic Acid Sodium Salt
U 53217A
PGI2,SODIUM SALT
Sodium PGI2
prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, monosodium salt, (5Z,9α,11α,13E,15S)-
PGI2-NA
PROSTAGLANDIN I2
Prostaglandin 12
PGI2 sodium
sodium (5Z)-5-{(3aR,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxyoct-1-en-1-yl]hexahydro-2H-cyclopenta[b]furan-2-ylidene}pentanoate
Epoprostenol sodium
Sodium (9α,11α,13E,15S)-11,15-dihydroxy-6,9-epoxyprosta-5,13-dien-1-oate

Chemical & Physical Properties

[ Boiling Point ]:
530.2ºC at 760mmHg

[ Melting Point ]:
168-170 °C

[ Molecular Formula ]:
C₂₀H₃₁NaO₅

[ Molecular Weight ]:
374.447

[ Flash Point ]:
182.1ºC

[ Exact Mass ]:
374.206909

[ PSA ]:
89.82000

[ LogP ]:
2.07380

[ Storage condition ]:
−20°C

[ Water Solubility ]:
H2O: 1 mg/mL Hydrolyzes to 6-ketoprostaglandin F1α in aqueous solution.

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332

[ Precautionary Statements ]:
P261-P280-P301 + P312 + P330

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S22-S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Gingival pain: an unusual side effect of ziprasidone.

BMJ Case Rep. 2013 , doi:10.1136/bcr-2012-007577, (2013)

The patient is a 52-year-old man with schizophrenia who developed severe, unremitting gingival pain after his ziprasidone dosage was increased from 80 to 120 mg. His physical examination and laborator...

PGI₂ signaling inhibits antigen uptake and increases migration of immature dendritic cells.

J. Leukoc. Biol. 94(1) , 77-88, (2013)

PGI₂ signaling through IP inhibits allergen-induced inflammatory responses in mice. We reported previously that PGI₂ analogs decreased proinflammatory cytokine and chemokine production by mature BMDCs...

Human follicular dendritic cells promote germinal center B cell survival by providing prostaglandins.

Mol. Immunol. 55(3-4) , 418-23, (2013)

Evidence for the immunoregulatory function of lipid molecules in addition to proteins is accumulating. Based on our previous reports on the production of prostaglandin E₂ (PGE₂) and prostacyclin by hu...