Methyl 4-aminobenzoate

Suppliers

Names

[ CAS No. ]:
619-45-4

[ Name ]:
Methyl 4-aminobenzoate

[Synonym ]:
Benzoic acid, 4-amino-, methyl ester
4-(Methoxycarbonyl)aniline
Methyl-4-aminobenzolcarboxylat
Benzoic acid,4-amino-,methyl ester
EINECS 210-598-7
Methyl 4-aminobenzoate
4-Aminobenzoic acid methyl ester
p-aminobenzoic acid methyl ester
Benzoic acid,p-amino-,methyl ester
p-(Methoxycarbonyl)aniline
METHYL P-AMINOBENZOATE
Methyl aniline-4-carboxylate
methyl 4-amino-benzoate
methyl ester of p-aminobenzoic acid
Methy-4-amino-benzoic acid
4-Carbomethoxyaniline
MFCD00007891

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
299.2±13.0 °C at 760 mmHg

[ Melting Point ]:
110-111 °C(lit.)

[ Molecular Formula ]:
C8H9NO2

[ Molecular Weight ]:
151.163

[ Flash Point ]:
154.9±17.4 °C

[ Exact Mass ]:
151.063324

[ PSA ]:
52.32000

[ LogP ]:
1.41

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.566

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG2900000
CHEMICAL NAME :
Benzoic acid, p-amino-, methyl ester
CAS REGISTRY NUMBER :
619-45-4
BEILSTEIN REFERENCE NO. :
0775913
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H9-N-O2
MOLECULAR WEIGHT :
151.18
WISWESSER LINE NOTATION :
ZR DVO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
237 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 17,900,1974

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S37/39-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DG2900000

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methanol
  • 4-Aminobenzoic acid
  • Methyl 4-chlorobenzoate
  • Methyl 4-amino-3-bromobenzoate
  • Methyl 4-bromobenzoate
  • Methyl 4-nitrobenzoate
  • Methyl 4-azidobenzoate
  • Methyl 4-boronobenzoate
  • 2-(4-methoxycarbonylphenoxy)propanamide
  • tert-Butyl 4-aminobenzoate

DownStream

  • methyl 4-(2-methylprop-2-enoylamino)benzoate
  • Methyl 4-(phenylsulfonamido)benzoate
  • Methyl 4-[(cyanoacetyl)amino]benzoate
  • Sodium 4-aminobenzoate
  • 2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-6-CARBOXYLIC ACID
  • 4-Amino-N-(2-hydroxyethyl)benzamide
  • methyl 3,5-diiodobenzoate
  • Methyl 4-amino-3,5-dichlorobenzoate
  • 4-METHOXYCARBONYLPHENYL ISOTHIOCYANATE
  • methyl 4-thiophen-2-ylbenzoate

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Tumor-preferential sustained drug release enhances antitumor activity of block copolymer micelles.

J. Drug Target. 22(7) , 619-28, (2014)

Nanoparticles are widely used as drug carriers for controlled, tumor-targeted delivery of various anticancer agents that have biopharmaceutical limitations such as water solubility and tissue permeabi...

Application of stripping voltammetry to trace lead analysis in intermediates and final products of syntheses of pharmaceuticals.

J. Pharm. Biomed. Anal. 14(7) , 765-71, (1996)

Applications of differential pulse anodic stripping voltammetry using a new pen-type renewed hanging mercury electrode have been investigated for trace analysis of lead in pharmaceutical substances an...

In Silico Estimation of Skin Concentration Following the Dermal Exposure to Chemicals.

Pharm. Res. 32 , 3965-74, (2015)

To develop an in silico method based on Fick's law of diffusion to estimate the skin concentration following dermal exposure to chemicals with a wide range of lipophilicity.Permeation experiments of v...


More Articles

Related Compounds

  • METHYL 4-AMINOBENZOATE HCL
  • diazonium salt of methyl 4-aminobenzoate
  • [1-(dimethylaminomethyl)cyclohexyl]methyl 4-aminobenzoate
  • [1-[(dimethylamino)methyl]cyclobutyl]methyl 4-aminobenzoate
  • [1-[(dimethylamino)methyl]cyclopentyl]methyl 4-aminobenzoate
  • ((3aR,4R,6R,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl 4-aminobenzoate
  • 4-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-fluorobenzoic acid
  • 1-(3-fluoro-phenyl)-3-methyl-1H-pyrazole-4-carbaldehyde
  • 3-Chloro-5-methoxymethoxypyridin-4-carbaldehyde
  • Thieno[2,3-c]pyridine-2-carboxamide,4-[(4-bromophenyl)amino]-
  • Thieno[2,3-c]pyridine-2-carboxamide,4-[3-[(cyclopropylmethyl)amino]phenyl]-
  • Thieno[2,3-c]pyridine-2-carboxamide,4-[3-[(4-pyridinylcarbonyl)amino]phenyl]-
  • 1-Cyclopropoxy-2-methylbenzene
  • Thieno[2,3-c]pyridine-2-carboxamide,4-[3-[[[2-(1-piperidinyl)ethyl]amino]methyl]phenyl]-
  • N-(4-bromophenyl)-4-fluorothieno[2,3-c]pyridine-2-carboxamide
  • Thieno[2,3-c]pyridine-2-carboxamide,4-[4-[(1h-pyrazol-1-ylacetyl)amino]phenyl]-
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.