(R,S)-4-Hydroxy Cyclophosphamide

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Names

[ CAS No. ]:
61903-30-8

[ Name ]:
(R,S)-4-Hydroxy Cyclophosphamide

[Synonym ]:
cis-4-hydroxycyclophosphamide
2H-1,3,2-Oxazaphosphorine, 2-(bis(2-chloroethyl)amino)-4-hydroxytetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorin-4-ol, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide
UNII:1XBF4E50HS
(R,S)-4-Hydroxy Cyclophosphamide,Preparation Kit
2-[Bis(2-chloroethyl)amino]-1,3,2-oxazaphosphinan-4-ol 2-oxide
(2R,4S)-rel-2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorin-4-ol 2-Oxide
4-Hydroxycyclophosphamide

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
387.1±52.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H15Cl2N2O3P

[ Molecular Weight ]:
277.085

[ Flash Point ]:
187.9±30.7 °C

[ Exact Mass ]:
276.019745

[ PSA ]:
71.61000

[ LogP ]:
-0.84

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.527

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • aldophosphamide
  • cis-Mosfosfamide
  • 4-Hydroperoxy cyclophosphamide

DownStream

  • aldophosphamide

Related Compounds

  • 7-<(R,S)-4-Hydroxy-2-methoxy-5-oxocyclopent-1-enyl>-(Z)-hept-5-ensaeure-methylester
  • 5,6-dihydro-(R,S)-4-hydroxy-(S)-6-methyl-4H-thieno[2,3-b]thiopyran 7,7-dioxide
  • 2-Allyl-4-hydroxy-3-methyl-2-cyclopenten-1-one
  • 4-[Hydroxy(1-trityl-1H-imidazol-4-yl)methyl]benzonitrile
  • (R,S)-Bode Kinetic Resolution Catalyst
  • (R/S)-4-(Aminomethyl)-3-pyrrolidinone O-Methyloxime Dichloride
  • 2-(2,3-dibromo-6-ethoxy-4-formylphenoxy)-N-(4-methylphenyl)acetamide
  • 2-(2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl)-8-(p-tolyl)-7,8-dihydroimidazo[2,1-c][1,2,4]triazine-3,4(2H,6H)-dione
  • 2-(2-(indolin-1-yl)-2-oxoethyl)-8-(p-tolyl)-7,8-dihydroimidazo[2,1-c][1,2,4]triazine-3,4(2H,6H)-dione
  • 2-(3,4-dioxo-8-(p-tolyl)-3,4,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazin-2(6H)-yl)-N-((tetrahydrofuran-2-yl)methyl)acetamide
  • 2-(2-chlorobenzyl)-8-(p-tolyl)-7,8-dihydroimidazo[2,1-c][1,2,4]triazine-3,4(2H,6H)-dione
  • Methyl 4-[[(1,2,3-trimethyl-1H-indol-5-yl)carbonyl]amino]benzoate
  • N-(4-acetamidophenyl)-2-((4-(2-(cyclohexylamino)-2-oxoethyl)thiazol-2-yl)thio)acetamide
  • 2-((4-(2-oxo-2-((4-sulfamoylphenyl)amino)ethyl)thiazol-2-yl)thio)-N-(p-tolyl)acetamide
  • 3-fluoro-N-(2-(6-(methylthio)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)benzamide
  • 4-fluoro-N-(2-(6-(methylthio)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)benzamide
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