2-Aminoisobutyric acid

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Names

[ CAS No. ]:
62-57-7

[ Name ]:
2-Aminoisobutyric acid

[Synonym ]:
a-Methylalanine
α-Methylalanine
2-amino-2-methylpropanoic acid
2-Aminoisobutyricacid
α-Aminoisobutyric acid
Alanine, 2-methyl-
2-Ammonio-2-methylpropanoate
EINECS 200-544-0
(α-methyl)alanine
a-Aminoisobutyric acid
2-Amino-2-methylpropionic acid
a-Aminoisobutanoic acid
2-methyl-2-aminopropanoic acid
2-Amino-2-MethylpropionicAcid
2-Aminoisobutyric Acid
Aib
MFCD00008049
NSC 16590

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
204.4±23.0 °C at 760 mmHg

[ Melting Point ]:
≥300 °C

[ Molecular Formula ]:
C4H9NO2

[ Molecular Weight ]:
103.120

[ Flash Point ]:
77.4±22.6 °C

[ Exact Mass ]:
103.063332

[ PSA ]:
63.32000

[ LogP ]:
-0.33

[ Vapour Pressure ]:
0.1±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.464

[ Storage condition ]:
Store at RT.

[ Water Solubility ]:
SOLUBLE

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AY7000000
CHEMICAL NAME :
Alanine, 2-methyl-
CAS REGISTRY NUMBER :
62-57-7
BEILSTEIN REFERENCE NO. :
0506496
LAST UPDATED :
199706
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C4-H9-N-O2
MOLECULAR WEIGHT :
103.14
WISWESSER LINE NOTATION :
ZX1&1&VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
C

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AY7000000

[ HS Code ]:
29224995

Precursor & DownStream

Precursor

  • Proc-Aib-OH
  • Alanine, 2-methyl-, methyl ester (6CI,7CI,8CI,9CI)
  • 5,5-Dimethylimidazolidine-2,4-dione
  • Sodium cyanide
  • Acetone
  • Alanine, N-benzoyl-2-methyl-
  • trichoderin B

DownStream

  • Alanine, 2-methyl-,ethyl ester
  • Alanine, N-(2-cyanoethyl)-2-methyl- (9CI)
  • H-Aib-OtBu.HCl
  • Fmoc-Aib-OH
  • Alanine, N,N,2-trimethyl- (9CI)
  • 2-Hydroxyisobutyric acid
  • isopropylamine
  • Alanine,2-methyl-N-(1-oxo-2-propen-1-yl)-
  • Alanine,2-methyl-N-(trifluoroacetyl)- (6CI,8CI,9CI)
  • ALPHA-AZIDOISOBUTYRIC ACID SOLUTION

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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Related Compounds

  • 2-Aminoisobutyric Acid
  • 2-Aminoisobutyric Acid
  • Boc-2-aminoisobutyric acid
  • Fmoc-2-Aminoisobutyric acid
  • N-formyl-2-aminoisobutyric acid
  • N-formyl-2-aminoisobutyric acid
  • benzyl N-[4-(4-bromophenyl)-1-methyl-1H-imidazol-5-yl]carbamate
  • benzyl N-[1-(3-bromophenyl)-3-methyl-1H-pyrazol-5-yl]carbamate
  • Methyl 7-bromo-3-{[(tert-butoxy)carbonyl]amino}-1-benzothiophene-2-carboxylate
  • Benzyl 3-(2-ethoxy-1,1-difluoro-2-oxoethyl)-3-hydroxyazetidine-1-carboxylate
  • 2-[(1,3-Dioxaindan-5-yl)[(benzyloxy)carbonyl]amino]acetic acid
  • 2-{[(Benzyloxy)carbonyl](phenyl)amino}propanedioic acid
  • tert-butyl N-[4-cyano-1-(4-nitrophenyl)-1H-pyrazol-5-yl]carbamate
  • tert-butyl N-[4-cyano-1-(2-nitrophenyl)-1H-pyrazol-3-yl]carbamate
  • 2-[N-(butan-2-yl)-2,2,2-trifluoroacetamido]-2,3-dihydro-1H-indene-2-carboxylic acid
  • 2-(3-Methylphenyl)-2-[1-(2,2,2-trifluoroacetyl)piperidin-4-yl]acetic acid